Influence of Psychotropic Drugs upon Neuropsychological Test Performance

Journal Title: International Neuropsychiatric Disease Journal - Year 2016, Vol 5, Issue 3

Abstract

Commonly used psychotropic medications are widely presumed to have deleterious effects on neuropsychological test performance. However, given the special difficulties of neuropsychological assessment with psychiatric populations, these effects have rarely been directly examined for differential, quantitative effects on test scores. A comprehensive neuropsychological test battery is described that assesses executive functions, memory, language comprehension, motor and sensory functions, and manual praxis. Data are presented on 233 psychiatric patients (70 females, 163 males) referred for neuropsychological assessment. All people with known or suspected brain damage were excluded, with 100 not taking any type of psychoactive medication. Comparisons between an unmedicated group and those taking the most common medications showed differences on tests of perseverative responses and praxis. No effects for nonverbal memory, simple motor functions, basic intellectual processes or visuomotor functions were noted. Implications for the assessment of people taking psychotropic medications are discussed.

Authors and Affiliations

Edward Helmes

Keywords

Related Articles

Roles of PI3K/AKT/PTEN Pathway in the Pathogenesis of Parkinson’s Disease and the Neuropsychiatric Symptoms

Parkinson's disease is a neurodegenerative disorder associated with loss of dopaminergic neurons in substantianigra caused by severe neuro-degeneration, which is the second most common neurodegenerative disorder after Al...

Childhood Onset Familial Nemaline Rod Myopathy: A Report of Two Siblings

Aims: Nemaline rod myopathy (NRM) is a rare form of congenital myopathy characterized by slowly progressive or non progressive muscle weakness and pathognomonic rod-like structures within the muscle fibers. Muscle weakne...

Social Support after Stroke: Influence of Source of Support on Stroke Survivors’ Health-Related Quality of Life

Introduction: Social support has often been identified as a key determinant of important stroke outcomes such as health-related quality of life (HRQoL). Information on the influence of the specific sources of social supp...

Pilot Study and Review: Physiological Differences in BDNF, a Potential Biomarker in Males and Females with Autistic Disorder

Aims: There is a need for more biologic research in autistic disorder (AD) to determine if biomarkers exist that would be useful for correlating to symptom severity and/or clinical improvement during treatment. Given the...

Tobacco Smoking and Medical Co-morbidities among Patients with Bipolar Disorder in a Nigerian Clinical Setting: A Case Control Study

Introduction: Smoking is highly prevalent in patients with bipolar disorder and is associated with medical and psychiatric comorbidities. The main aims of this study were to determine the prevalence and correlates of smo...

Download PDF file
  • EP ID EP241694
  • DOI 10.9734/INDJ/2016/20422
  • Views 114
  • Downloads 0

How To Cite

Edward Helmes (2016). Influence of Psychotropic Drugs upon Neuropsychological Test Performance. International Neuropsychiatric Disease Journal, 5(3), 1-10. https://europub.co.uk/articles/-A-241694