Influence of the formulation and preparation technique on the flufenamic acid release from different collagenic supports designed for wound healing
Journal Title: Proceedings of the International Conference on Advanced Materials and Systems (ICAMS) - Year 2018, Vol 1, Issue
Abstract
Drug delivery systems with controlled release are one of the top applications for human health, a new domain in material science with biomedical application. The aim of this study was to obtain and characterize some drug delivery systems based on collagen, dextran and flufenamic acid (matrices, membranes and fibers) for wound healing. The samples were analyzed by FT-IR and in vitro release of flufenamic acid. From the FT-IR spectra it can be seen that collagen macromolecule keeps its triple helix structure. The percentage of drug delivered is influenced by the degree of cross linking, the presence of dextran in the designed formulations and the collagen support preparation technique.
Authors and Affiliations
Maria Minodora Marin, Ştefania Marin, Elena Dănilă, Mădălina Georgiana ALBU KAYA, Mihaela Violeta GHICA, Lăcrămioara Popa, Răzvan Mihai Prisada, Gheorghe Coară, Ciprian CHELARU
Keywords
Related Articles
- EP ID EP602513
- DOI 10.24264/icams-2018.I.19
- Views 108
- Downloads 0
Agrotextile systems - strategic elements for sustainable development of the agriculture
“Agriculture is the backbone of our country; Textile can be the backbone of Agriculture?” Today, agriculture and horticulture has realized the need of tomorrow and opting for various technologies to get higher overall yi...
In-situ modified antimony-film glassy carbon electrode for metal trace analysis
Glassy carbon electrodes (GCE) have been extensively employed for the determination of trace amounts of heavy metals. Lately, modifications of GCE are currently being sought. One way of obtaining better analytical perfor...
Undergarment PPE with modular structure for staff working in the national defense, public order and security system
The protection of operational staff from defense, public order, security structures, with a personal protective equipment system adequate to the conditions of execution of specific missions is a major desiderate for opti...
Synergistic activities of Hypericum perforatum L. and glabridin against drug resistant H. pylori isolates
Glabridin and Hypericum perforatum L. have many pharmacological activities such as antimicrobial activity, antiproliferative, cytotoxic, anticancerogenic, antiproliferative and antioxidant effect. The aim of this study w...
The status of leather supply chain in Egypt: an exploratory study for the INNOLEA project
Egypt has a traditional wealth in manufacture and use of leather and leather products as demonstrated on the walls of the tombs of pharaonic civilization. Nowadays the status of leather supply chain in Egypt has deterior...