Influence of thermolysis in the nitrogen medium on physicochemical properties of medical using material based on biogenic hydroxyapatite
Journal Title: Хімія, фізика та технологія поверхні - Year 2017, Vol 8, Issue 1
Abstract
Physicochemical properties and adsorbtion activity of biogenic hydroxyapatite-based (BHA) osteoapatite material and BHA alloyed by ferromagnetic particles due to using two methods of physicochemical mixing with subsequently low-temperature thermolysis in a nitrogen medium at 500 °C (below the Curie point for magnetite – 572 °C) for 2 h have been studied. The phase composition of the powders was determined using an X-ray diffractometer DRON 3.0 under CoKα-radiation. According to X-ray studies, the material obtained by including BHA directly in the process of iron oxalate preparation had a higher intensity of Fe3O4 than such peaks of the material obtained through mechanical mixing of BHA microgranules with iron oxalate. X-ray analysis data agreed well with the data of chemical analysis which showed the Fe content of 1.17 mass. % and 1.12 mass. % at a first and second case respectively. Data of scanning microscope Jeol Superprobe 733 are evidence of uniform distribution of magnetite in BHA matrix in the both materials. Solubility experiments were performed in vitro in isotonic 0.9 % solution of NaCl with using the BHA microgranules and the powders of BHA alloyed by ferromagnetic particles placed in an incubator for 2 and 7 days at the temperature 36.6–37 °C, corresponding to the normal temperature of the human body. Both alloyed materials showed a biosolubility higher than that in BHA microgranules for the first 2 days and almost identic value for all powders after 7 days. To avoid an infection from implanted osteoapatite materials, adsorption of antibiotics is carried out by different methods. However, it is reasonable to check adsorption activity of such biomaterials preliminary for test indicators with molecular mass like that of necessary medicaments. In particular, the investigated materials were checked by using methylene blue (320 g/mol). According to the results of experiments, the presence of the alloying element influences on the adsorption properties of the investigated biomaterials at the specified concentration of methylene blue compounds solution insignificantly.
Authors and Affiliations
O. M. Otychenko, T. E. Babutina, O. R. Parkhomey, L. S. Protsenko, I. V. Uvarova
Keywords
Related Articles
- EP ID EP247319
- DOI 10.15407/hftp08.01.010
- Views 141
- Downloads 0
Removal of uranyl cations from iron-containing solutions using compositesorbents based on polymer matrix
Some technologies of uranium recovery from minerals involve hydrochloric acid where cationic forms of uranyl ions dominate. The work is devoted to development and testing of sorbents for removal of uranium(VI) from liqui...
Фізико-механічні властивості органо-неорганічних композитів на основі поліуретану, силікату натрію та Zn-Al шаруватих подвійних гідроксидів
Mетою даної роботи було створення органо-неорганічних композитів (ОНК) поліуретану, що містять силікат натрію та Zn-Al шаруваті подвійні гідроксиди (ШПГ). Органічною матрицею було вибрано макродіізоціанат (МДІ) на основі...
Електрофізичні властивості композитів на основі епоксидної смоли та терморозширеного графіту
Розроблено полімерні конструкційні матеріали на основі епоксидної смоли, терморозширеного графіту (ТРГ) та наповнювачів неорганічної природи – перліту, вермікуліту з покращеними електрофізичними характеристиками. З метою...
Room-temperature gas sensor based on semiconductor nanoscale heterostructures ZnS/CdS
Nanoscale heterostructures ZnS/CdS have been synthesized in order to put into effect those gas sensors, which work at room temperature. Synthesis was carried out in two stages. The first stage is the formation of CdS nan...
Effects of methods and basis sets on calculation results using various solvation models
Effects of methods and basis sets on calculation results using various solvation models