Influence of Vitamin D Level on Diabetic Dyslipidemia
Journal Title: Asian Journal of Medicine and Health - Year 2017, Vol 7, Issue 1
Abstract
Background: Vitamin D deficiency is greater than expected all over the world and it is linked to many health and disease conditions. Aim of the Work: Our work aimed to study the relation between serum level of vitamin D 25( OH ) and lipid parameters. Patients and Methods: This study included 176 participants 88 patients with type 2 diabetes mellitus and 88 clinically healthy volunteers age and sex matched persons with normal glycated hemoglobin as a control group and their age ranged from 30 to 60 years old. A full history and clinical examination were done for both patients and control group. Fasting samples (12hrs) for lipid parameters including total cholesterol, triglycerides, (HDL) and (LDH), serum 25 (OH) vitamin D level ,fasting blood sugar and 2 hour postprandial and (HbA1c). Results: In this study 71 patients had vitamin D deficiency (80.7%) and 17(19.3%) patients had either vitamin D insufficiency or sufficiency. Compared to the control group which showed that 38 persons had deficient vitamin D (43.2%) and 50 (56.8%) had either vitamin D insufficiency or sufficiency, which demonstrate that there were high statistical significance difference between case and controls regarding to 25(OH)D with p-value <0.001. Although in diabetic patients with vitamin D deficiency, serum levels of total cholesterol, TG, and LDL were higher and HDL was lower compared to patients with vitamin D sufficiency, this association was statistically significant for serum level of TG (237.3 ± 120.9 vs. 186.3 ± 77.0), and HDL (33.5 ± 6.4 vs. 40.4 ± 13.2), with P=0.037 and 0.003, respectively. Also in the control group there was a statistically significant difference between participants with vitamin D deficiency when compared to those without regarding the mean values of triglycerides (257.4 ± 106.2 vs. 155.8 ± 108.9), and HDL (30.7 ± 10.1 vs. 44.3 ± 15.5), with P<0.0001. This study also revealed that there was a negative statistically significant correlation between vitamin D level and HbA1C (P=0.035) in diabetic group. Conclusions: The results of the present study showed that serum concentrations of 25(OH) D were inversely associated with high TG and low HDL in both diabetics and control groups.
Authors and Affiliations
Mohamed Mashahit, Alaa Elsayed, Hala Eltoukhy
Keywords
Related Articles
- EP ID EP336746
- DOI 10.9734/AJMAH/2017/36086
- Views 77
- Downloads 0
Anxiety and Visual Field Assessment Reliability in Glaucoma Patients
Background: Visual field assessment is very important for the diagnosis and monitoring of glaucoma. Anxiety may affect the quality of a patient’s performance when undergoing these assessment tests and influence the relia...
Seroprevalence of Helicobacter pylori Ig G Antibody and Risk Factors in Hypertensive Patients at Dschang District Hospital in Cameroon
Aims: Growing evidence suggests that certain extragastric diseases were associated with Helicobacter pylori infection. This study aimed to determine the seroprevalence of H. pylori Ig G antibody and risk factors among hy...
Visfatin Level in Diabetic and Non-diabetic Chronic Kidney Diseases
Introduction: Chronic kidney disease (CKD) has become a global public health threat. The irreversible nature of the disease, its association with significant morbidity and mortality as well as the cost of renal replaceme...
Lifestyle Diseases: Knowledge and Related Practice among Residents of Uyo Metropolis
Aim: The study was aimed at determining the knowledge of some lifestyle diseases such as stroke, hypertension, diabetes, chronic obstructive pulmonary diseases and obesity by residents of Uyo Metropolis, and their practi...
Standardization of Jala Peenisa Choornam Used for Peenisa Rogam
Indigenous Medicine of Sri Lanka consists of Ayurveda, Siddha and Unani Medicines. Herbal drugs are commonly used in Siddha Medicine. Peenisa Rogam is one of the common diseases of neck and above. Jala Peenisa choornam (...