Erythema Annulare Centrifugum and Relapsing Polychondritis Associated with Acute Myeloid Leukemia: A Case Report

To the Editor, Erythema annulare centrifugum (EAC) is a slow progressing and recurring skin disease with unknown etiology, characterized by ring shaped erythematous skin rashes. EAC was first described by Darier in 1916...

Gaucher Disease and Gaucher Cells

 Hidroksiüre İlişkili Mavi Lunula

The Accelerated Phase of Chediak-Higashi Syndrome: The Importance of Hematological Evaluation

Chediak-Higashi syndrome is a rare autosomal recessive disease that was first described in 1943 by Bequez-Cesar in 3 siblings that bore the primary clinical features. In 1952 Chediak (a Cuban hematologist) and in 1954 Hi...

ABL gene kinase domain mutation scanning by denaturing high performance liquid chromatography sequencing method

Objective: Despite the efficacy of the BCR-ABL tyrosine kinase inhibitor imatinib, the development of resistance against imatinib has been observed. The most important mechanisms known to cause resistance are point mutat...