Information about Prostate Cancer for Urologist: Ga-68 Prostate Specific Membrane Antigen Positron Emission Tomography/Computed Tomography Scintigraphy
Journal Title: Üroonkoloji Bülteni - Year 2016, Vol 15, Issue 4
Abstract
Recently, prostate-specific membrane antigen (PSMA), a glutamate carboxypeptidase II enzyme, has transformed intoan excited radiopharmaceutical agent as a result of radiolabeling of small peptides that are developed for the inhibition of this enzyme. Studies performed with Ga-68 PSMA positron emission tomography/computed tomography (CT) scintigraphy revealed an intensive involvement of this agent in prostate cancer itself and in the metastasis of lymph nodes, bones and organs. Positive rates associated with prostate-specific antigen levels were detected in the ratio of approximately 80% especially in patients with biochemical relapse. The sensitivity was found to be better than both CT and magnetic resonance imaging, and F18 choline as well. There are also findings that might be considered as successful for the staging of indication. Lu-177 PSMA might be affective in patients resistant to castration as being specific to prostate cancer.
Authors and Affiliations
Levent Kabasakal
Keywords
Related Articles
- EP ID EP228360
- DOI 10.4274/uob.616
- Views 66
- Downloads 0
The Presence and Thickness of Pseudocapsule after Partial Nephrectomy in Renal Cell Carcinoma
Objective: In this study, we aimed to evaluate the presence and thickness of pseudocapsule after partial nephrectomy in renal cell carcinoma (RCC) cases. Materials and Methods: A total of 100 patients who were admitted t...
Robotic-assisted Laparoscopic Prostatectomy: Initial Experience of 267 Cases
Objective: To present our experience of 267 consecutive patients treated with robotic-assisted laparoscopic prostatectomy (RALP) and assess the perioperative and postoperative outcomes. Materials and Methods: Materials a...
Partial Urethrectomy for Female Urethral Transitional Epithelial Cell Carcinoma
To present a female case of partial urethrectomy and the following adjuvant chemo-radio-therapy for urethral transitional epithelial cell carcinoma originating from distal urethra in the light of literature. The patient...
University of Health Sciences, İzmir Bozyaka Training and Research Hospital, Clinic of Urology, İzmir, Turkey
Granulomatous prostatitis, first described by Tanner and McDonald in 1943, is a histopathological diagnosis that includes mixed type inflammation with granulomas in the prostatic tissue. Granulomatous prostatitis compris...
Ablation Therapies in Small Renal Masses
Small renal masses are defined as renal neoplasms with the largest diameter less than 4 cm and the incidence of renal malignancies is increased with the widespread use of cross-sectional imaging methods. One of the optio...