INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION IN-VITRO BY VARIOUS EXTRACTS OF HYPTIS SUAVEOLENS (L.) POIT.
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 3
Abstract
Hyptis suaveolens (L) Poit. commonly known as Vilayati tulsi, belongs to the Mint family Lamiaceae. The inhibition of in-vitro calcium-oxalate crystal (a major component of most urinary stones) formation by various extracts of Hyptis was investigated by titrimetric method. The inhibitor potency of alcohol extracts of Hyptis suaveolens (L.) Poit was found to be comparable to that of cystone (a proprietary drug for dissolving kidney stones). Thus alcohol extract could be further analyzed in vivo and further characterization of its active compound could lead to the discovery of a new candidate drug for the patients with urolithiasis.
Authors and Affiliations
Kumkum Agarwal , Ranjana Varma
Keywords
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