INHIBITION OF PROTEASES AND ANTI-CANCER ACTIVITIES OF ETHANOLIC TUBER EXTRACT OF GLOBBA BULBIFERA
Journal Title: International Journal of Pharmacognosy - Year 2014, Vol 1, Issue 1
Abstract
Studies on anticancer and protein inhibition process play a vital role in regulating the cellular process of life and diseases. The present studies have been conducted on ethanolic tuber extract from Globba bulbifera for protease inhibition and breast cancer inhibition. The extract has shown good inhibition for Trypsin, Chymotrypsin and protease K. The extract has also shown MCF-7 (Breast Cancer) inhibition, IC50 value at 235 μg/ml. The inhibition is less compared to the standard compound, tamoxifen (IC50: 37 μg/ml). Hence the present studies have shown good protease inhibition and anticancer (breast cancer) activities.
Authors and Affiliations
Narasinga Rao V
Keywords
Related Articles
- EP ID EP427100
- DOI -
- Views 95
- Downloads 0
SENNA OCCIDENTALIS SEED: IS IT HEALTH RISK OR POTENTIAL MEDICINE?
In resource-limited localities of developing countries, potentially manageable, if not useful, resources may present actual health and agricultural cost due to poor management and lack of awareness of health risk consequ...
CHEMICAL CONSTITUENTS FROM THE AERIAL PARTS OF LANTANA INDICA ROXB.
Lantana indica Roxb. (Verbenaceae) is grown as an ornamental plant in tropical and subtropical regions of the world. The plant is used to treat asthma, abdominal disorders, bilious fever, cancer, catarrhal infections, ch...
PHYSICO-CHEMICAL CHANGES THAT OCCURS DURING FERMENTATION OF ARISHTAM (A HYDRO ALCOHOLIC CLASS OF DRUG OF AYURVEDA)
The present study was to evaluate the physicochemical changes that take place in vasarishta during the manufacturing of the arishtams (hydro-alcohol class of drug of Ayurveda). The manufacturing process of the Arishtams...
PHYTOCHEMISTRY AND PHARMACOLOGY OF THREE PIPER SPECIES: AN UPDATE
In this review, the current knowledge on the phytochemistry and pharmacology of Piper betle (betel), Piper sarmentosum (wild pepper) and Piper caninum (wild betel) is updated with some description of their botany and use...
COMPOSITIONS, DISTRIBUTIONS AND STATUS OF ECONOMIC PLANTS AMONG INVASIVE FLORAS OF UTTARPARA, WEST BENGAL, INDIA
A survey was carried out from 2005 to 2010 to invent the invasive alien plant species and their economic uses in urban and adjoining rural areas of Uttarpara, Hooghly district, West Bengal. The study revealed the occurre...