Insulin is a Gift of Life for People With Diabetes
Journal Title: Diabetes Research – Open Journal - Year 2015, Vol 1, Issue 2
Abstract
Although Diabetes Mellitus (DM) or sugar diabetes was identified centuries ago, it was not known why this metabolic disorder develops until JR Macleod and Frederick Banting made the discovery. DM is due to deficiency of insulin produced by beta cells of the pancreas. Prior to this discovery and its application around 1921, many people with this disorder died from diabetic coma. Thus insulin made a milestone in the treatment of DM, in early part of the 20th century and it is the same today. However, commercialism prevails in the care of DM with too much twist in the therapy. It is now the norm to prescribe oral anti-diabetic agents in all adults with diabetes called Type 2 DM. Oral anti-diabetic drugs lower fasting blood glucose and HbA1c but not 2h postprandial blood glucose. The latter is related to diabetic complications. Thus, although patients are not dying from diabetic coma because of insulin but they are developing whole gamut of complications which have increased the morbidity and mortality in patients with DM. Thus the emphasis of this article is to resurge the use of insulin as a gift of life for patients with DM and a therapy which permits a healthy and active life for them.
Authors and Affiliations
Anil K. Mandal
Regulatory T-Cells in Treatment of Type-1 Diabetes: Types and Approaches
Regulatory T-cells (Tregs) play important role in regulation of immune responses to self-antigens. Alterations in frequency and function of Tregs have been reported in Type 1 Diabetes (T1D) subjects. Tregs have the poten...
Current Controversies around Carbohydrate Restriction and the Risk of High-Protein Diets
Recently, a Low carbohydrate (LCH) diet has been recommended by many doctors to control hyperglycemia and overweight. Unlike a traditional calorie-restricted diet, a carbohydrate-restricted diet typically contains less t...
Type 1 Diabetes Update at Children With Diabetes Community
Of the estimated 415 million people living with diabetes worldwide, 10% have Type 1 Diabetes (T1D) meaning they will remain insulin dependent until a cure is found. Globally, we can observe an increasing trend of about 5...
Increasing Adherence to the Diabetes Regimen: An Occupational Therapy Perspective
Recognizing the epidemic of diabetes in the United States, the Centers for Disease Control projected that as many as one third of the population will have diabetes by 2050, without a concerted effort to change the lifest...
Wellness Fasting and Hyperketosis
Ketoacidosis is sometimes a lethal complication of diabetes mellitus.1-3 Ketone bodies are considered to be the toxic elements of ketoacidosis. Wilder3 considered that the threshold of ketogenesis (i.e. the maximal rati...