Insulin Oedema in Newly Diagnosed Type 1 Diabetes Mellitus
Journal Title: Journal of Clinical Research in Pediatric Endocrinology - Year 2010, Vol 2, Issue 1
Abstract
Despite the essential role of insulin in the management of patients with insulin deficiency, insulin use can lead to adverse effects such as hypoglycaemia and weight gain. Rarely, crucial fluid retention can occur with insulin therapy, resulting in an oedematous condition. Peripheral or generalised oedema is an extremely rare complication of insulin therapy in the absence of heart, liver or renal involvement. It has been reported in newly diagnosed type 1 diabetes, in poorly controlled type 2 diabetes following the initiation of insulin therapy, and in underweight patients on large doses of insulin. The oedema occurs shortly after the initiation of intensive insulin therapy. We describe two adolescent girls with newly diagnosed type 1 diabetes, who presented with oedema of the lower extremities approximately one week after the initiation of insulin treatment; other causes of oedema were excluded. Spontaneous recovery was observed in both patients.
Authors and Affiliations
Veysel Baş, Semra Çetinkaya, Sebahat Ağladıoğlu, Havva Nur Kendirci, Hatice Bilgili, Nurdan Yıldırım, Zehra Aycan
Keywords
Related Articles
- EP ID EP84727
- DOI -
- Views 162
- Downloads 0
Growth Hormone Replacement Therapy: Transition from Adolescence to Adulthood
Consideration of GH re-testing should be performed in all adolescents reaching the transition period (if not at start of puberty) who had been previously diagnosed with idiopathic, isolated GH deficiency. In the presence...
Hypophosphatasia Presenting with Pyridoxine-Responsive Seizures, Hypercalcemia, and Pseudotumor Cerebri: Case Report
Hypophosphatasia (HPP) is an inborn error of metabolism characterized by defective bone mineralization caused by a deficiency in alkaline phosphatase (ALP) activity due to mutations in the tissue-nonspecific ALP (TNALP)...
Vitamin D Deficiency in Children and Adolescents with Type 1 Diabetes
Ob­jec­ti­ve: To investigate the frequency and effects of vitamin D deficiency in children with type 1 diabetes (T1D) in a region which is known to have a high rate of vitamin D deficiency among adolescents....
Ghrelin Levels and Postnatal Growth in Healthy Infants 0-3 Months of Age
Objective: The effect of ghrelin on growth of the newborn has long been argued, but not fully clarified. In this study, we aimed to investigate the relationship between ghrelin levels and growth parameters in the first 3...
Melnick-Needles Syndrome Associated with Growth Hormone Deficiency: A Case Report
Melnick-Needles syndrome is an X-linked dominant bone dysplasia characterized by a typical facies (exophthalmos, full cheeks, micrognathia, and malalignment of teeth), flaring of the metaphyses of long bones, s-like curv...