Insulinoma - Rare, But Important Clinical Problem. Analysis of a Series of 530 Patients Who Underwent Surgical Treatment for the Pancreatic Tumor

Journal Title: Polish Journal of Surgery - Year 2014, Vol 86, Issue 11

Abstract

Insulinomas are rare tumors, accounting for 1‑2% of all neoplasms of the pancreas. Usually their treatment is not associated with any problems; however there is a small subset of problematic clinical cases. The authors present their own clinical experience with surgical treatment of insulinomas of the pancreas. The aim of the study was to conduct a retrospective analysis of patients with insulinomas of the pancreas who underwent surgical treatment at Department of General and Transplant Surgery Medical University in Łódź. Material and methods. The study included all patients who underwent surgical treatment at the Department between 2007 and 2013 for the tumor of the pancreas. Further retrospective analysis included all patients with tumors of the insulinoma type. The data was obtained from medical records, surgical protocols and histopathology reports. Results. The analysis included 530 patients who underwent surgical treatment for the tumor of the pancreas. Insulinoma was found in 10 (1.88%) patients (8 females, 2 males). An average age of patients who underwent surgical treatment was 47.5±13.8 years. An average size of the tumor was 1.6±0.5 cm. Six patients underwent extirpation of the insulinoma, while the other patients underwent distal resection of the pancreas. All patients underwent “an open surgical procedure”. The average duration of the surgical procedure was 55±45 minutes. Duration of the hospitalization in the analyzed group of patients was 7±5 days. Incidence of postoperative pancreatic fistulas was 10%. All insulinomas were benign. Conclusions. Insulinomas were rare among patients who underwent surgical treatment at the Department. They were benign and their treatment was unproblematic. However, there is a small group of cases that can be associated with problematic clinical situations. Thus treatment of patients with insulinomas should be conducted at specialist centers. Correct diagnostic and therapeutic management, involving close cooperation between multiple medical specialists, results in complete curing of majority of patients.

Authors and Affiliations

Adam Durczyński, Piotr Hogendorf, Dariusz Szymański, Witold Izdebski, Aleksandra Kaczka, Łukasz Durko, Janusz Strzelczyk

Keywords

Related Articles

Splenic artery pseudoaneurysm rupture into a pancreatic pseudocyst with its subsequent perforation as the cause of a massive intra-abdominal bleeding – case report

Pseudocysts account for approximately 70% of all cystic lesions of the pancreas. One of the most dangerous complications of pancreatic pseudocysts is bleeding into the cystic lumen; the most common cause of the bleeding...

Mammotome biopsy in diagnosing and treatment of intraductal papilloma of the breast

Intraductal papilloma is a benign breast tumor which needs histopathological verification because of the risk of cancer coincidence. The aim of the study was to assess the value of the mammography-guided and ultrasound-g...

Association of Polymorphism of Lys589glu Exo1 Gene with the Risk of Colorectal Cancer in the Polish Population

The incidence of colorectal cancer (CRC) is increasing from year to year. Despite intensive research CRC etiology remains unknown. Studies suggest that at the basis of the process of carcinogenesis can lie reduced effici...

Laparoscopy-Assisted Total Gastrectomy with D2 Lymphadenectomy and Roux-En-Y Reconstruction - Case Report

We report a case of patient with stage IIIb gastric cancer qualified for laparoscopy – assisted gastrectomy and our first impressions about this procedure. Total gastrectomy with complete omentectomy and extended lymphad...

Download PDF file
  • EP ID EP74354
  • DOI 10.2478/pjs-2014-0090
  • Views 113
  • Downloads 0

How To Cite

Adam Durczyński, Piotr Hogendorf, Dariusz Szymański, Witold Izdebski, Aleksandra Kaczka, Łukasz Durko, Janusz Strzelczyk (2014). Insulinoma - Rare, But Important Clinical Problem. Analysis of a Series of 530 Patients Who Underwent Surgical Treatment for the Pancreatic Tumor. Polish Journal of Surgery, 86(11), 505-510. https://europub.co.uk/articles/-A-74354