INTERPRETATION OF HISTOGRAMS AND ITS CORRELATION WITH PERIPHERAL SMEAR FINDINGS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 60
Abstract
BACKGROUND The blood cell counters have evolved over a decade from 3 parts to 5 parts and presently even 7 parts differential cell counters have stepped into the haematopathology world. These cell counters generate histograms, which are a graphic representation of different population cell types and are a neglected piece of information by haematopathologist. The present study to the best of our knowledge is first of its kind in Indian scenario, which throws light on indispensable information generated by the histogram flags and their respective concurrence with peripheral smear findings. MATERIALS AND METHODS The study is conducted on haematology histograms for RBC, WBC and platelets generated by 3-part cell counter by Sysmex KX-21 and their degree of concurrence and non-concurrence with (Giemsa stained) peripheral smear findings respectively. Study DesignIt is a descriptive study of 100 cases being studied at central clinical laboratory, Department of Pathology, Government Medical College, Surat. RESULTS A 100% concurrence was found between RU, PU, WU and F1, F2, F3 flags and their peripheral smear findings. The degree of nonconcurrence varied from 10.6% (T2 flag) to 20% (WL flag). CONCLUSION The principle causes of non-concurrence as concluded by the study are predominantly preanalytical errors as EDTA induced platelet clumps and high background electrical noise leading to generation of erroneous flags. The other causes include activated cells (Lymphocytes), large giant platelets or polychromatophilic erythrocytes.
Authors and Affiliations
Ashish Gupta, Pragya Gupta, Bhaghat V. M
Keywords
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- EP ID EP226827
- DOI 10.14260/Jemds/2017/955
- Views 85
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