Interrelationship of serum TSH with BMI in patients with thyroid disorders
Journal Title: International Journal of Medical Research and Review - Year 2016, Vol 4, Issue 6
Abstract
Introduction: The endocrine system is evaluated primarily by measuring hormone concentrations, thereby arming the clinician with valuable diagnostic information. Thyroid Hormones which increase the basal metabolic rate and thermogenesis have been reported to be one of leptins regulating factors because alterations of thyroid status might lead to compensatory changes in circulatory leptin. Aim: The aim of this study was to find the correlation of Serum TSH with BMI in patients with thyroid disorder (hypothyroidism and hyperthyroidism). Material & Methods: 30 diagnosed cases of thyroid disorders out of which 20 were of hypothyroidism and 10 were of hyperthyroidism and 30 healthy controls were recruited in our study. Serum TSH levels were estimated in both cases and controls using ELISA method. BMI was calculated using QUETLET’S index as body weight (kg) divided by height squared (m2). Results: In our study we found a significant (p=<0.001) positive correlation (r=0.514) of TSH with BMI in hypothyroid patients whereas a non significant (p=.551) positive correlation (r=.215) was found in hyperthyroid patients. Conclusion: Even small changes in the TSH levels can have an effect on BMI profile. In hypothyroid patients there is increase in weight so increase in BMI and also increase in TSH. On the other hand in hyperthyroid individuals there is loss of weight so decrease in BMI and also decrease in TSH. But further large scale data is required to confirm our findings.
Authors and Affiliations
Gesu Singla, G K Bedi, H S Sandhu, Chittranjan Vij
Keywords
Related Articles
- EP ID EP230198
- DOI 10.17511
- Views 120
- Downloads 0
High Sensitivity C-Reactive Protein an inflammatory marker and lipoprotein levels in patients with coronary heart disease
Background: C-Reactive Protein is a good marker of systemic inflammation which can be measured easily. Atherosclerosis lesions are intimal thickening of arteries. Inflammatory and immune cells constitute an important par...
A rare case of primary umbilical endometriosis in a nulliparous female confirmed on imaging and histopathology: Case report
Endometriosis is a common gynaecological condition, the pelvis being the most common site. Extrapelvic sites including intestinal tract, urinary tract, omentum, thorax, surgical scars and umbilicus are less common sites...
Importance of ultrasound investigation in the early prenatal diagnosis of an Oral-Facial-Digital Syndrome Type I: a new case report
We report a case of a 29 year old female. Ultrasound examination showed a fetus with: cleft lip and cleft palate, ocular hypertelorism, polydactyly and polycystic kidney. Amniocentesis was performed and the fetal chromos...
A prospective, randomized, double blind controlled trial of the use of preoperative antibiotics in routine abdominal surgery: A comparative analysis between Ofloxacin + Metronidazole, Cefotaxime + Sulbactum and Cefepime +Tazobactum (Single does vs. Three doses) and their effects.
Introduction: Anti microbial prophylaxis before any elective surgery is a preferred deterrent to post operative surgical site infection now. We have used different antibiotics, two being from the cephalosporin class, one...
Pattern of admissions into the newborn unit of university of Uyo Teaching Hospital, Nigeria
Background: Neonatal conditions have been noted to contribute significantly to under-five mortality rate. Knowledge of its pattern in our environment will help in planning for improved health care delivery. Aim: To deter...