INTESTINAL AND EXTRAINTESTINAL MANIFESTATIONS OF CROHN’S DISEASE- A CROSSSECTIONAL STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 30
Abstract
BACKGROUND Crohn’s disease is a chronic idiopathic inflammatory bowel disease, which remained neglected till 1980s. The clinical presentation of Crohn's disease vary considerably from subtle abdominal discomfort to bleeding per rectum. Factors contributing to this variability include the location of disease within the gastrointestinal tract, the intensity of inflammation and the presence of specific intestinal and extraintestinal complications. There is a rising incidence and prevalence of Crohn’s disease in India, which may be associated with numerous risk factors. MATERIALS AND METHODS This study included consecutive patients with a diagnosis of Crohn’s disease attending Government Medical College, Thrissur, from 1st September, 2010, to 31st January, 2012. Patient’s demographic data, physical examination, laboratory and endoscopic findings were recorded and analysed. RESULTS Fifteen patients (males 6 and females 9) were registered with Crohn's, the age ranging from 17 yrs. to 73 yrs. The mean age of onset was 36 years with the male-female ratio as 1:1.5. Among the 15 patients, 80% had insidious onset of abdominal pain, 66.7% had loose stools as a presentation with streaky blood and mucus in stool, 27% had more than 4 episodes of loose stools per day and 93% had weight loss at presentation. CONCLUSION The mean age of onset of symptoms was found to be 36 years and a male:female ratio was 1:1.5. Crohn’s disease may present with subtle symptoms to acute abdomen, mucus diarrhoea, blood in stools and abdominal pain are common presentations of Crohn's disease.
Authors and Affiliations
Renny Issac, Amar Jayanthi Anandam, Muraly Cheruparambil Pengan
Keywords
Related Articles
- EP ID EP217908
- DOI 10.18410/jebmh/2017/348
- Views 96
- Downloads 0
OCULAR MANIFESTATIONS IN DIABETES-RELATED CHRONIC RENAL FAILURE PATIENTS IN A TERTIARY CARE CENTRE
BACKGROUND A descriptive, observational and non-interventional hospital-based study on diabetes-related chronic renal failure patients undergoing regular haemodialysis was conducted to evaluate the occurrences of ocular...
ROLE OF FIBEROPTIC BRONCHOSCOPY IN PATIENTS WITH SPUTUM SMEAR NEGATIVE FOR ACID FAST BACILLI AND CHEST XRAY SUGGESTIVE OF PULMONARY TUBERCULOSIS
AIMS: To study the role of fiberoptic bronchoscopy in patients with sputum smear negative for AFB and chest X-ray suggestive of pulmonary tuberculosis. SETTINGS AND DESIGN: After informed consent, 60 adult patients with...
EARLY POST-OPERATIVE PROSTHETIC FITTING PROBLEMS AND SCOPE IN EARLY REHABILITATION
BACKGROUND Limb loss is one of the most physically and psychologically devastating events that can happen in a person. Successful rehabilitation following amputation is complex and requires multiple medical, surgical and...
NIPPLE AREOLA COMPLEX INVOLVEMENT IN EARLY AND LATE CARCINOMA BREAST
The last several decades have witnessed significant advances in the surgical management of carcinoma breast. Many have embraced breast conservation as the procedure of choice in carefully selected patients. It provides e...
BIOMETRY OF MANDIBLE
BACKGROUND The purpose of study of biometry of mandible is to evaluate the sex of the individual by statistically significant various parameters of the mandible and also a few selected landmark points on the mandible. MA...