INTESTINAL NEURONAL DYSPLASIA, TYPE B - A CASE REPORT
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 15
Abstract
Intestinal neuronal dysplasia (IND) is one of the conditions known to mimic Hirschsprung’s disease (HD) both clinically and radiologically, and clinically presents with intestinal obstruction in pediatric age group. Two types are described.1 IND Type A is characterized by a malformation of the adrenergic nerve supply to the blood vessels and IND Type B, in which the submucosal plexus is involved. Giant ganglia are involved in Type B, and there is abnormal morphology of the nerve cell groups and nerve cell fibres.2 In the present case, diagnosis was established mainly by biopsy and microscopic examination of H&E stained sections, which show increased ganglion cells both in number and size, and confirmed by Cathepsin D immunostaining.
Authors and Affiliations
Lakshmi Vasavi H, Kiran Kumar E
Keywords
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- EP ID EP227153
- DOI 10.18410/jebmh/2015/331
- Views 84
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