Intra-articular injection of bone marrow concentrate protocol for Osteoarthritis – A preliminary report with 12 months follow up

Journal Title: IP International Journal of Orthopaedic Rheumatology - Year 2017, Vol 3, Issue 1

Abstract

Osteoarthritis – a degenerative joint disorder by loss of cartilage leading to pain and physical function of the patients. Most existing Intra articular injections show promising results in pain relief but none have regenerative potentials. With the existing published evidences and clinical trial an attempt was made by Intra articular injection of autologous bone marrow concentrate in 10 Osteoarthritis patients with 12 months follow up. Bone marrow was concentrated using protocols of Biosafe Sepax and on an average 7ml of concentrate was injected in each defective knee. Patients showed improvements by pain relief and physical function. Apart from WOMAC pain score and VAS the improvement was also found in increase of joint space and cartilage volume evident from post-operative X ray and MRI, which might be due to the regeneration of cartilage. No adverse events were noted in this study

Authors and Affiliations

VR Ravi, Avinash Gandhi, S. Sankaranarayanan, K. Manimaran

Keywords

Related Articles

Use of a semi-precision attachment to fabricate a removable partial denture – a case report

Use of attachments in providing better retention to removable prosthesis is not an outdated treatment modality. It is important for dentists to have more updated knowledge about its use and the success of such prosthesis...

Primary Hypertrophic Osteoarthropathy and successful treatment with Oral Bisphosphonates: A Case Report with Literature Review

Abstract Primary hypertrophic osteoarthropathy (PHOA) is a rare syndrome with diverse radiological and clinical features. Though the diagnosis can be easily made on the basis of the classic clinical and radiological feat...

A hidden cause of troublesome bone pain in an adult-Brodie’s abscess

Introduction Brodie abscess (subacute osteomyelitis) is an infectious disease localized in metaphyseal bone(1). Brodie first described a localized abscess of the tibia in an amputated limb that did not produce systemic s...

Efficacy of synovial fluid analysis and synovial biopsy in diagnosing joint pathologies

Introduction Joint disease is a common orthopaedic problem They often occur in younger people and tend to be destructive This can lead to widespread disability and morbidity Diagnosis is clinical aided with conventional...

Osteochondroma of proximal end fibula causing common peroneal nerve compression: A rare case presentation

Osteochondroma is ectopic calcification in physeal plate causing a bony outgrowth with a cartilage cap. Osteochondroma grows till the growth plate is open. Osteochondroma constitutes 10% of all bone tumours and, among th...

Download PDF file
  • EP ID EP298401
  • DOI 10.18231/2455-6777 .2017.0002
  • Views 80
  • Downloads 0

How To Cite

VR Ravi, Avinash Gandhi, S. Sankaranarayanan, K. Manimaran (2017). Intra-articular injection of bone marrow concentrate protocol for Osteoarthritis – A preliminary report with 12 months follow up. IP International Journal of Orthopaedic Rheumatology, 3(1), 8-14. https://europub.co.uk/articles/-A-298401