Intra-Ventricular Tumors and Their Expression with Immunohistochemistry (IHC) Markers- Original Article

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Intra-Ventricular Tumors and Their Expression with Immunohistochemistry (IHC) Markers- Original Article

Journal Title: Saudi Journal of Pathology and Microbiology - Year 2017, Vol 2, Issue 4

Abstract

Abstract: Intraventricular neoplasms of the central nervous system are rare and arise from periventricular structures such as the walls of the ventricular system, the septum pellucidum, and the choroid plexus. Many tumour types arise from, or can bulge into the ventricular system, although there are certain lesions that are relatively restricted to ventricles. A number of factors assist in defining the differential diagnosis, both radiological and clinical, including where the lesion is positioned within the ventricle as well as age and any associated conditions. A total of 30 cases of primary intraventricular tumors were studied. Study included both the left over squash and regular tumor tissue specimen. Duration of the study was 2 years. In this study, the overall incidence of the intraventricular tumors was 5.47 %, 30 cases among the total 548 intracranial lesions. Out of the 30 cases, 19 were males and 11 were females. Most of the cases were seen in the age group of 11 to 20 years and least tumors were seen in the age group 51 to 70 years. Intraventricular tumors are rare tumors and they closely mimic various other tumors of the CNS on imaging. Squash cytology and Histopathological examination (HPE) usually confirms the diagnosis. Keywords: Intraventricular, Neoplasms, Medulloblastoma, Meningioma, Choroid Plexus Papilloma, Neurocytoma, Glial Fibrillary Acidic Protein, Synaptophysin.

Authors and Affiliations

Anunayi Jestadi, Kandukuri Mahesh Kumar

Keywords

Intraventricular Neoplasms Medulloblastoma Meningioma Choroid Plexus Papilloma Neurocytoma Glial Fibrillary Acidic Protein Synaptophysin.

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EP ID EP386296
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