Intracervical dinoprostone versus sublingual misoprostol for preinduction ripening of cervix
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2017, Vol 4, Issue 1
Abstract
Objective: To compare the efficacy of intracervical dinoprostone and sublingual misoprostol in preinduction cervical ripening. Study design: This prospective observational study was performed on 410 women with medical or obstetrical indications for labour induction. On an alternative basis, women were selected for intracervical dinoprostone and sublingual misoprostol for pre-induction cervical ripening. 0.5 milligram of dinoprostone was placed intracervically every 6-12 hours for a maximum of three doses in one group and 25 microgram of misoprostol was given sublingually, every 4 hours for a maximum of five doses in the other group. Mean number of doses required, induction to active phase interval, induction to delivery interval, need for oxytocin augmentation, mean cost and neonatal outcomes were analyzed. Statistical analysis was done using SPSS 17 version software. Statistical significance was considered as 0.05 level (P value). Results: There was no significant difference in the mean number of doses required with regard to Bishop’s score when misoprostol was used, but significant difference was there when dinoprostone was used. There was no statistically significant difference in induction to active phase interval, induction to delivery interval and neonatal outcomes between the two groups. There was significantly higher failed induction in dinoprostone group. There was significantly lesser oxytocin requirement in misoprostol group. Mean cost was 37.75 times greater in dinoprostone group. Conclusion: 25 microgram of sublingual misoprostol provides a cheaper alternative method to intracervical dinoprostone for induction of labour.
Authors and Affiliations
Jaya Vijaya Raghavan, Sheila K. Pillai, Dilshath Meera
Keywords
Related Articles
- EP ID EP313028
- DOI 10.18231/2394-2754.2017.0015
- Views 81
- Downloads 0
Role of Bacterial Vaginosis in threatened preterm and preterm labour, and its screening
Background: 8-10% pregnancies end in preterm labour or threatened preterm labour which has maternal and foetal complications just due to infections such as bacterial vaginosis, which can be identified by simple tests lik...
Evaluation of Umbilical Cord Coiling Index in late second trimester and its association with Perinatal Outcome
Background: Umbilical cord plays a major role for foetal persistence during the intrauterine period. Reports had shown that abnormal umbilical cord coiling in the form of hypo or hypercoiling are associated with abnormal...
Study on bone health in postmenopausal women at a tertiary care hospital
Objectives 1 To find the prevalence of musculoskeletal symptoms after menopause 2 To evaluate the densitometry findings in menopausal patients presenting with musculoskeletal symptoms 3 To know the effect of duration of...
Role of who modified partograph in management of spontaneous labour in primigravidas
Introduction Pregnancy and child birth though considered as physiological process can become lethal for any woman Childbirth was considered as rebirth to a woman in olden era The atmost duty of an Obstetrician is to iden...
Effect of oral iron and intravenous iron sucrose on pregnancy related outcome among pregnant females with iron deficiency anemia
Introduction Intravenous iron sucrose and oral iron therapy are the primary therapeutic modalities for management of iron deficiency anaemia during pregnancy but its efficacy during pregnancy is still a matter of argumen...