Intracorneal Amphotericin B Injection in a Case of Indolent Candidal Keratitis
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 5
Abstract
Ocular candidiasis is one of the opportunistic infection occurring in human body. Pathogenesis wise, Candida is very virulent and slow growing organism. We report a case of 76-year-old female with left eye candidal stromal abscess, not responding to topical and oral antifungal drugs. Patient was administered intrastromal amphotericin B injection in the affected eye. Four midstromal injections were given in the areas surrounding the corneal abscess. A total of approximately 0.05 mL of amphotericin B, 5 μg per 0.1 mL, was administered. Within next four weeks, the eye became completely quiet with healed epithelial defect and corneal scarring. Intracorneal injection of amphotericin B is a safe and effective treatment option for recurrent and recalcitrant fungal infections.
Authors and Affiliations
Jyoti Deswal, Sudesh Kumar Arya
Keywords
Related Articles
- EP ID EP342435
- DOI 10.7860/JCDR/2017/23249.9774
- Views 82
- Downloads 0
Intraosseous Epidermal Inclusion Cyst of the Great Toe: Masquerading as Bone Tumour
Images in Medicine
Assessment of Depression and Social Support in Elderly Subjects Residing in an Old Age Home: A Pilot Study
ABSTRACT Introduction: Depression and lack of social support, particularly in institutionalised elderly population forms a major cause of concern. The problem statement of which in the current scenario, if precisely asse...
Scrub Typhus Complicated by Acute Respiratory Distress Syndrome and Haemophagocytic Lymphohistiocytosis in a Young Patient
ABSTRACT Scrub typhus is an endemic rickettsial disease causing vasculitis involving the small vessels of the body. Haemophagocytic Lymphohistiocytosis (HLH) is a hyperinflammatory syndrome characterised by excessive unb...
Prevention of Severe Tongue Biting in a Mentally Challenged Patient: A Clinical Report
ABSTRACT Orofacial dysfunctions and habits are the main factors which influence the development of malocclusion and perioral disease. In this context, Orthodontics, a field of Dentistry, is closely associated with the d...
Opioid Sparing Effect of Anaesthesia on Postoperative Inflammatory Cytokine Response in Oral Cancer Surgery
ABSTRACT Introduction: Dexmedetomidine is a potent and highly selective alpha-2 adrenoreceptor agonist with the unique sedative, analgesic, perioperative sympatholytic, anaesthetic-sparing and haemodynamic-stabilizing pr...