Intracranial Ependymomas in Children: The Role of Surgery And Adjuvant Treatment.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
The management of pediatric intracranial meningiomas poses a big challenge. We are presenting the role of extent of tumor resection and adjuvant therapy in the survival of children with ependymomas. This is a retrospective study of 56 children with non-metastatic intracranial ependymomas treated between 2010 and 2015.The mean age was 8 years ranging between 3 months and 15 years.The most frequent location was infra tentorial location in 67.8% of patients. Total tumor resection was possible in 42.8% (25 patients)while partial resection was performed in 35.7%More than half of the patients were between WHO histological grade I and II (Grade I: 12 patients and Grade II: 18 patients) while 44.6% of tumors were anaplasic ependymomas (Grade III: 25 patients). More than half of the patients have received radiotherapy as initial adjuvant treatment (55.3%), while less than half of all patients have received chemotherapy (21.4%). Four children have received radiotherapy and chemotherapy.Morbidity experienced included six patients CSF leakage, four patients meningitis and nine patients with neurologic deterioration, 2 patients with seizures and 2 patients with intraventricular hemorrhage. There were four deaths after 38 months follow up and all our patients were followed up for 05 years.
Authors and Affiliations
K. Bouaita, Shabay. Z, N. N. Ioualalen
Keywords
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- EP ID EP588158
- DOI 10.9790/0853-160101120126
- Views 70
- Downloads 0
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