Intracranial Plasmacytoma with Unilateral Vision Loss: An Unusual Initial Presentation of Multiple Myeloma
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 10
Abstract
Plasma cell neoplasms are clonal proliferation of plasma cells that produce a single class of immunoglobulin. Among the plasma cell neoplasms, both solitary plasmacytoma of bone and extra-osseous plasmacytoma can progress to multiple myeloma. Here, we described a rare case of multiple myeloma with initial presentation as plasmacytoma with both intracranial and extracranial component, sphenoid sinus involvement and left sided vision loss. Serum protein electrophoresis revealed presence of M spike. Histopathological and immunohistochemical analysis detected plasmacytoma. Extramedullary plasmacytoma is a rare presentation of multiple myeloma. Intracranial involvement and involvement of sphenoid sinus of plasmacytoma with pressure effect mimicking other intracranial neoplasm is extremely rare. Clinicians should consider this entity in any solitary intracranial neoplasm with rapid progression of clinical course
Authors and Affiliations
Malay Sarkar
Keywords
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