Intraoperative requirement of Phenylephrine for spinal anaesthesia, with comparison of hemodynamic parameters between severe pre-eclamptic and normotensive parturients for elective caesarean section: A prospective study
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 1
Abstract
Aim: The aim of this study is to assess the efficacy and safety of spinal anaesthesia by comparing the severity of hypotension and intraoperative requirement of Phenylephrine to treat it in severe pre-eclamptic and normotensive parturients undergoing elective caesarean section. Materials and Methods: A total of 50 parturients, 25 each of normotensive and pre-eclamptic were given spinal anaesthesia with 12.5mg of hyperbaric bupivacaine after preloading with 10ml/kg of Ringer lactate solution. The vitals namely heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and the mean arterial blood pressure (MAP) were monitored during caesarean section. Severity of hypotension and the mean requirement of Phenylephrine to manage this hypotension were compared in the two groups. Foetal outcome was compared in two groups by studying the Apgar score. Results: There was statistically less hypotension following spinal anaesthesia and less requirement of vasopressor in pre-eclamptic as compared to normotensive parturients. The mean requirement of Phenylephrine was 156.3±62µg in normotensive (group I) and comparatively more than the requirements of pre-eclamptic (group II) parturients and was statistically significant (p<0.05). The Apgar score at 1 and 5 minutes were equal in both the groups. Conclusion: Spinal anaesthesia is ideal and safe option for severe pre eclamptics undergoing elective caesarean section without any additional risk to baby.
Authors and Affiliations
Leena Goel, Rina Cordeiro, Megha Goel
Keywords
Related Articles
- EP ID EP472991
- DOI 10.18231/2394-4994.2018.0021
- Views 46
- Downloads 0
Effect of minimal cuff inflation with thermo softening of the endotracheal tube to minimize the trauma during naso tracheal intubation – observational study
Introduction and Objective: Several techniques and modifications have been to put forward to decrease the decrease nasopharyngeal trauma and epistaxis. This study evaluated the effect on partial inflation of the thermo s...
Comparison of oral metoprolol versus telmisartan premedication on blood loss and hypotensive anesthesia in patients treated for Orthognathic Surgery
Purpose: This study was aimed to compare blood pressure reducing effects of oral metoprolol versus telmisartan premedication as adjuvant to fentanyl and sevoflurane on various parameters of anesthesia during orthognathic...
Role of nitroglycerine as tocolytic agent during double valve replacement surgery in pregnant patient with successful fetal outcome
Cardiovascular disease is an important non-obstetric cause of maternal and fetal morbidity and mortality during pregnancy. Cardiac surgery during pregnancy is usually well tolerated by mother but the fetal outcome is var...
A prospective randomized double-blind controlled trial on evaluating the Efficacy of Inj.Metoprolol 50µgm/Kg. I.V., in attenuating the hemodynamic response to laryngoscopy, intubation and carbon dioxide pneumoperitoneum in patients undergoing laparoscopic appendicectomy
Introduction: We evaluated the efficacy of inj.Metoprolol 50 µgms/kg. i.v. given 5 minutes before induction of anesthesia in attenuating the hemodynamic response to intubation and CO2 pneumoperitoneum. Materials and Meth...
A comparative study of intrathecal clonidine VS dexmedetomidine in caesarean patients
Introduction: Spinal anaesthesia is the most commonly employed technique for Caesarean section. Many drugs such as opioids as intrathecal additives such have been widely studied found to be associated with respiratory de...