INTRATHECAL FENTANYL VERSUS DEXMEDETOMIDINE AS ADJUVANTS TO HYPERBARIC BUPIVACAINE IN INFRAUMBILICAL SURGERIES
Journal Title: IJAR-Indian Journal of Applied Research - Year 2018, Vol 8, Issue 6
Abstract
The study evaluated and compared the efficacy of intrathecal fentanyl 25μg and dexmedetomidine 5μg with 0.5% hyperbaric bupivacaine. Each study group consisted of 25 patients. Patients were randomly divided to receive intrathecally either 0.5% hyperbaric bupivacaine 3ml+0.5 ml of normal saline (control Group B) or (Group F) 0.5% hyperbaric bupivacaine 3ml+25μg fentanyl or (Group D) 0.5% hyperbaric bupivacaine 3ml+5μg dexmedetomidine. Peak sensory level achieved, time to reach Bromage 3, time to two segment regression, regression to Bromage 0, hemodynamic stability, time to rescue analgesia, total analgesic consumption in first 24hrs were recorded. Results: The peak sensory level reached were T6-T7 (32%) in Group B, whereas T4-T5(44%) in Group F and T4-T5(72%) in Group D. The mean time to regression to Bromage 0 in Group B was 119.60±11.72 min, 159.20±9.09 min in Group F, 402.00±18.71 min in Group D. The mean time to rescue analgesia in Group B was 136.00±5.00 min, 182.40±8.79 min in Group F and 396.40±17.77 min. Total dose of analgesic consumption in Group B was 228±34.10mg, 105±37.50mg in Group F and Group D was 81±20.77mg. Side effects among the groups were found be not significant statistically (P=0.935)
Authors and Affiliations
Dr Amrutha S, Dr. Narayanaswamy D. K
Keywords
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