Intravaginal misoprostol for medical management of missed abortions up to twenty weeks of gestation
Journal Title: Santosh University Journal of Health Sciences - Year 2018, Vol 4, Issue 2
Abstract
Introduction Missed abortion is a type of abortion in which the dead fetus is retained within the uterus The objective of the study was to find out whether the use of one or two doses of 800 g misoprostol alone administered intravaginally is effective and safe in termination of missed abortion up to 20 weeks of pregnancyMaterials and Methods This Interventional study was conducted in a tertiary care hospital for a period of 12 months Sample size consisted of 67 cases of missed abortion up to 20 weeks of pregnancy which was confirmed by ultrasound These patients were given 800g misoprostol and were followed up for successful termination of pregnancy and side effects viz pain excessive bleeding need for surgical evacuation rupture uterus and infection If complete abortion had not been attained by a single dose a repeat dose of 800g vaginal misoprostol was insertedResults In the present study 8806 patients aborted completely after giving misoprostol alone where as 729 patients requiring only single dose of misoprostol The success rate decreased with increasing parity and number of previous abortions in patients and results were found statistically significant p 0008 and 0035 respectively Side effects were tolerable and required only proper counselingConclusion Misoprostol alone is a safe and effective method of termination of missed abortion up to 20 weeks of gestation and will prove to be a good alternative to surgical management Keywords Missed abortion Misoprostol Intravaginally Termination of pregnancy 20 weeks gestation Surgical evacuation
Authors and Affiliations
Neelima Agarwal, Manisha Gupta, Alpana Agrawal, Rashmi Saxena, Divya Shubham
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