Intravenous Fat Emulsion (IFE) Improvement of Qt-Interval in Tricyclic Antidepressant Overdose
Journal Title: Emergency Medicine – Open Journal - Year 2016, Vol 2, Issue 2
Abstract
Here we report a case of a 62-year-old female with a potentially lethal ingestion of a tricyclic antidepressant (nortriptyline) refractory to conventional therapy. In the emergency department, she was profoundly hypotensive and significantly acidotic. She received several sodium bicarbonate boluses followed by continuous sodium bicarbonate infusion in addition to multiple vasopressors. Despite these measures, the patient remained dangerously hypotensive with a prolonged QT interval. Lipid emulsion was started with a bolus and infusion. Subsequently, the patient successfully weaned off pressor support and her QT interval normalized. After a short hospital course, patient was discharged with only moderate cognitive impairment.
Authors and Affiliations
Ryan Mason
Keywords
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- EP ID EP548249
- DOI 10.17140/EMOJ-2-124
- Views 124
- Downloads 0
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