Intravenous fluid supplementation as treatment modality in severe nonhemolytic neonatal hyperbilirubinemia
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 3
Abstract
Introduction: Neonatal jaundice is a common problem and researchers have always tried to find treatment modalities which can prevent exchange transfusion in neonates with significant jaundice. Fluid supplementation has been tried in significant neonatal jaundice nearing exchange levels in different doses and durations. The present study was undertaken to assess the efficacy of i.v. fluid supplementation (0.33 DNS) in non hemolytic significant neonatal jaundice. Methods: This study was performed in Department of Paediatrics, Bebe Nanki Mother and Child Care Centre, Govt. Medical College, Amritsar, Punjab for a period of 15 months. Seventy two healthy term neonates with indirect non hemolytic hyperbilirubinemia were assigned randomly to receive either only breastfeed (group B ; n=36) or i.v. fluids for 8 hrs in addition to breastfeed (group A ; n=36). The rate of decrease of total serum bilirubin(TSB), total duration of phototherapy and need of exchange transfusion were compared. Results: The fall in TSB in initial 8 hrs was 3.27±1.18 mg/dl in group A versus 2.16±0.90 mg/dl in group B (p=0.001). The duration of phototherapy or hospital stay was also shorter in group A i.e. 44.25±3.29 hrs versus 53.11±5.96 hrs in group B (p=0.001). Only 1 neonate required exchange transfusion from group B while none from group A required exchange transfusion (p=0.314). Conclusion: I.v. fluid supplementation in severe non hemolytic hyperbilirubinemia significantly decreases TSB, total duration of phototherapy or hospital stay with no impact on need for exchange transfusion.
Authors and Affiliations
Dr Ramandeep Kaur,Dr Narinder Singh,Dr Palwinder Singh,Dr MS Pannu, Dr Karnail Singh, Dr Ashwani Kumar,Dr NS Neki,
Keywords
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- EP ID EP563351
- DOI 10.22192/ijcrms.2018.04.03.007
- Views 114
- Downloads 0
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