Inverse Association between Vitamin D Status and Diabetes in a Clinic Based Sample of Hispanic Adults in Puerto Rico
Journal Title: Diabetes Research – Open Journal - Year 2015, Vol 1, Issue 1
Abstract
Background: Vitamin D deficiency is a public health problem around the world. Diabetes has been associated with vitamin D deficiency. We aimed to examine the association between the vitamin D status and diabetes in a clinic based sample of Hispanic adults in Puerto Rico. Methods: Demographics and laboratory test results for serum 25(OH)D, Fasting Blood Glucose (FBG), and Haemoglobin A1C (HbA1c) were extracted from medical records. Vitamin D status was classified as deficient (<12 ng/ml); inadequate (12-20 ng/ml); insufficient (21-29 ng/ ml) and optimal (≥30 ng/ml) using serum 25(OH)D levels. Results: A total of 716 records were included in the analyses. Most were females (63.3%), with mean age of 54.1±14.9 y, mean BMI 30.1±6.3 kg/m2 and mean serum 25(OH)D levels of 24.3±8.6 ng/ml. Most were classified as diabetics (41.1%). Those with diabetes had lower 25(OH)D levels compared to pre-diabetic and normal glucose status (p<0.05). Serum 25(OH) D levels were inversely correlated to FBG and HbA1c in the total sample and in men (p<0.05). After adjusting for age, gender, BMI and seasonality, there was a greater risk of diabetes, but not prediabetes, in those with serum 25(OH)D levels <30 ng/ml. This risk increased from 1.8 times in those with vitamin D insufficiency to 4.2 times in those with vitamin D deficiency (<12 ng/ml). Conclusion: Diabetes risk significantly increased as serum 25(OH)D levels decreased in this group of Hispanic adults, underscoring the importance of routinely screening high risk individuals for vitamin D deficiency and offer supplementation to normalize serum levels.
Authors and Affiliations
Cristina Palacios
Keywords
Related Articles
- EP ID EP549955
- DOI 10.17140/DROJ-1-102
- Views 145
- Downloads 0
Impaired Awareness of Hypoglycemia and Driving Mishaps in Patients With Type 1 Diabetes Mellitus: A Multi-Center Survey in Japan
Impaired Awareness of Hypoglycemia (IAH) is a common and serious problem in adult patients with Type 1 Diabetes Mellitus (T1DM). Driving accidents related to hypoglycemia have been previously described. The aim of this s...
Increasing Adherence to the Diabetes Regimen: An Occupational Therapy Perspective
Recognizing the epidemic of diabetes in the United States, the Centers for Disease Control projected that as many as one third of the population will have diabetes by 2050, without a concerted effort to change the lifest...
Effect of Low Carbohydrate Diet on Type 2 Diabetic Patients and Usefulness of M-Value
Background: Debate between the Calorie Restriction (CR) and Low-Carbohydrate Diet (LCD) has been continued for several years. We have started LCD therapy for diabetic patients since 1999, and experienced good response to...
Clinical and Experimental Evidence of Hypoglycemic Neuropathy
When compared with the extensive research on hypoglycemic impacts on Central Nervous System (CNS) and cardiovascular system, the effects of hypoglycemia on the Peripheral Nervous System (PNS) have not been investigated a...
Type 1 Diabetic and Hypertensive Retinopathy: Case Presentation and Review of Literature
Background: Type 1 Diabetes (T1D) Mellitus is a complex, chronic illness that affects half a million children under the age of 15 years. Complications associated with diabetic retinopathy can be prevented with continued...