Investigating the effect of ghrelin on improving memory and learning ability in animals: A systematic review
Journal Title: Journal of Current Biomedical Reports - Year 2021, Vol 2, Issue 2
Ghrelin does an important role in neurological functions such as memory, learning, and cognition as well. There is some evidence that ghrelin can improve memory. This study aimed to evaluate the effects of ghrelin on rat memory. A systematic search was conducted to identify papers published by Iranian authors in the Web of Science, PubMed, Scopus, Embase, and Google Scholar electronic databases from January 2010 to December 2019 with the PRISMA statement. Totally, 547 animals were listed in our systematic review. All of the animals were male Wistar rats with a mean weight of 250±280 g. The Morris Water Behavior behavioral test and the passive avoidance task were performed to evaluate memory. Truly, injection of ghrelin appears to enhance the compactness of the synapse dendritic spines in the hypothalamus. These findings indicate that ghrelin has a prospective role to recover learning and memory ability in animal models, suggesting it as a candidate therapy for memory.
Authors and Affiliations
Mohaya Farzin, Parastoo Jafarzade, Niloofar Faraji, Seyedeh Maral Mousavi, Mostafa Yousefi
Coronavirus is a beta virus that has caused a worldwide pandemic since December 2019. Many treatments such as antiviral drugs, immunosuppressive drugs, neutralizing antibodies, and monoclonal antibodies have been tested...
Case reports in the use of vitamin C based regimen in prophylaxis and management of COVID-19 among Nigerians
This case study was based on the novel opinion that daily intake of vitamin C can serve as a prophylactic and curative intervention for the coronavirus disease of 2019 (COVID-19) via homeostatic and epigenetic mechanisms...
Detection of carbapenem resistance and virulence genes among Acinetobacter baumannii isolated from hospital environments in center of Iran
Carbapenem-resistant Acinetobacter baumannii are the top urgent antibiotic resistance threat in the world. The aims of this study were the determination of carbapenem-resistant genes and virulence genes among isolates fr...
HIV has been introduced as a causative agent for AIDS which is still considered as a major health problem for the country and a burden on the health care system. Raising awareness and knowledge plays a critical role in c...
Akkermansia muciniphila is an anaerobic species of gut microbiome that has been proposed as a new functional microbiota with probiotic properties. Recent research has shown the amazing abilities of probiotic bacteria, A....
How To Cite
Mohaya Farzin, Parastoo Jafarzade, Niloofar Faraji, Seyedeh Maral Mousavi, Mostafa Yousefi (2021). Investigating the effect of ghrelin on improving memory and learning ability in animals: A systematic review. Journal of Current Biomedical Reports, 2(2), -. https://europub.co.uk/articles/-A-694715