Investigation of Adaptation to Successive Postural Perturbations in Patients with Multiple Sclerosis
Journal Title: Turkish Journal of Neurology - Year 2020, Vol 26, Issue 1
Abstract
Objective: It is well known that abnormal automatic postural responses impair balance control in patients with multiple sclerosis (PwMS) and these responses can be ameliorated with training. However, the difference between patients with MS and the healthy population on the adaptation capacity of postural responses to perturbations remains unclear. The aim of the present study was to evaluate the adaptation capability to postural perturbations in PwMS and to reveal differences between healthy controls. Materials and Methods: Sixty-nine ambulatory PwMS with Expanded Disability Status Scale (EDSS) scores below or equal to 5.5, and 61 healthy subjects were recruited for the study. Adaptation Test with NeuroCom Smart Balance Master System, Berg Balance Scale (BBS), and EDSS were administered. The adaptation test was performed in the toes-up and toes-down directions; five consecutive perturbations were given for each direction. The sway energy score was calculated for postural sway that were released during these perturbations. Results: According to the adaptation test results, healthy volunteers’ sway energy scores were significantly lower than those of PwMS in five consecutive perturbations (toes-up p<0.001, toes-down p<0.001). Healthy volunteers and PwMS were adapted in trial 3 for both directions and sway energy score changes in time were found similar between the groups. The toes-up adaptation rate in PwMS (17%) was statistically lower than in healthy group (31%) (p=0.026), and the toes-down adaptation rate was similar (p=0.175). The BBS and EDSS had significant correlations with average toes-up sway energy scores (r=-0.402, r=0.392, respectively). Conclusion: Ambulatory PwMS have preserved adaptation to automatic postural responses, with higher sway energy scores. A low adaptation rate in the toes-up direction should be taking into account when planning the motor strategy training.
Authors and Affiliations
Yeliz Salcı, Ecem Karanfil, Ender Ayvat, Ayla Fil Balkan, Jale Karakaya, Songül Aksoy, Kadriye Armutlu, Aslı Tuncer, Rana Karabudak
Keywords
Related Articles
- EP ID EP685126
- DOI 10.4274/tnd.2019.34392
- Views 169
- Downloads 0
Twelfth Cranial Nerve Involvement in Guillain-Barre Syndrome: A Case Report
Guillain-Barre syndrome (GBS) is a common neurologic disease with paresthesia, albuminocytologic dissociation in cerebrospinal fluid analysis, accompanied by motor weakness, areflexia/hyporeflexia and mild sensory loss....
Neurobrucellosis: Two Cases, Two Different Presentation
Brucellosis is an infectious disease seen particularly in developing countries with a high rate of morbidity. It can affect any system in the body and lead to different clinical presentations. The patients presented here...
Palliative Care Requirement in Neurologic Diseases
Objective: It has been reported that the need for palliative care (PC) increases every day in chronic critical illnesses such as neurologic disorders. We investigated the demographics and comorbidities of neurological pa...
Cerebral Venous Thrombosis Can Be Followed by Electroencephalography: Accompanied By a Case Discussion
no summary
Relationship Between Alcohol Type and Posterior Reversible Encephalopathy Syndrome: A Case Report
Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiologic syndrome characterized by headaches, altered mental status, seizures, visual symptoms, hallucinations, focal neurologic signs, and vasogenic ed...