Investigation of Cytotoxic Effects of Inula Viscosa Extract
Journal Title: Cumhuriyet Science journal - Year 2019, Vol 40, Issue 3
Abstract
Inula viscosa is a type of Asteraceae family, which widely used for medicinal plant to treatment of different diseases. Inula viscosa contains many biological compounds, such as monoterpenes, sesquiterpenes, diterpenes, flavonoids. Our study aimed to investigate the cytotoxic effects of Inula viscosa extract on MCF-7 (breast carcinoma), C6 (glioblostoma cancer), MG63 (bone osteosarcoma), cancer cells and L929 (mouse fibroblostama) cell lines. Cytotoxic effects of the Inula viscosa extracts were performed by XTT assay. In this study, Inula viscosa extracts showed selective cytotoxic effect on MC-7 compared than L929 cells. The Inula viscosa extracts appear to be a promising source of new anticancer agent. Further studies are needed to identify the cytotoxic activity mechanisms on these cancer cell lines.
Authors and Affiliations
Ceylan Hepokur, Yakup Budak, Hasan basri Karayel, Bedrettin Selvi, İlhan Yaylım
Keywords
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- EP ID EP663180
- DOI 10.17776/csj.437993
- Views 60
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