INVESTIGATION OF SOME CHEMICAL CONSTITUENTS AND ANTIOXIDANT ACTIVITY OF ASPARAGUS SPERNGERI
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 11
Abstract
Objective: Asparagus sprengeri (A S) is an ornamental plant cultivated in EGYPT. This study was designed to investigate some lipid and flavanoid constituents, in addition to the evaluation of antioxidant activity of different extracts of the plant.Methods: Two phospholipid were identified by (HPTLC). The fatty acid methyl ester and unsaponifiable matter were analyzed by GC. Four flavonoids were isolated by CC and purified by PPc. Identification of isolated flavanoidal compounds was carried by spectroscopic analysis Viz, TLC,PC, UV, EL-MS and H-1– NMR. The different extracts were tested for their free radical scavenging activity using DPPH and β-Carotene- linoleic acid bleaching assay.Results: Four flavonoids, were isolated, apigenin, dihydroquercitin, naringenin, apigenin- 7-o- glucoside Nine fatty acids, Myrestic and linoliec acids were the major components. The unsaponifiable matter was found to be a mixture of hydrocarbons from (C13– C28) and cholesterol two classes of phospholipid were identified namely L-α-Phosphatidyl-DL-glycerol and L-α- Phosphatidylethanolamine. The alcoholic extract of the plant has moderate antioxidant activity with EC50 0.114 and 0.110 mg/ml for the DppH and β-carotene methods respectivelyConclusion: Asparagus sprengeri can be used as the natural antioxidant. Flavonoids are suggested to be a group of key antioxidants in Asparagus.Â
Authors and Affiliations
Rasmia Aly Hassan, Wafaa A. Tawfeek, Amera A. Habeeb, Magda S. Mohamed, Khaled, A. Abdelshafeek
Keywords
Related Articles
- EP ID EP579258
- DOI -
- Views 87
- Downloads 0
COLON SPECIFIC DELIVERY OF EUDRAGIT E-100 AND EUDRAGIT-FS30D COATED TABLETS OF LEFLUNOMIDE USING CHITOSAN-CHONDROITIN SULPHATE INTERPOLYMER COMPLEX
Objectives: In the present study, site specific colonic drug delivery system was developed on the principles of the combination of pH and microbially triggered controlled system.Methods: The basic design consists of chit...
IDENTIFICATION AND ANALYSIS OF ADVERSE DRUG REACTIONS ASSOCIATED WITH CANCER CHEMOTHERAPY IN HOSPITALIZED PATIENTS
Objective: To analyze the incidence of adverse drug reactions (ADRs) associated with chemotherapeutic drugs and study its management. Methods: A prospective observational study was carried out on hospitalized patients un...
PHYSICO-CHEMICAL CHARACTERISTICS OF RUSSIAN TEA FUNGUS: KOMBUCHA
Objective: To characterize various physicochemical parameters for Russian tea fungus: Kombucha. Methods: In the present investigation, various physicochemical analyses of kombucha such as, estimation of biomass, ascorbic...
ANTIMICROBIAL POTENTIALOF HEMOLYMPH AND HEPATOPANCREAS OFPORTUNUSSEGNISCRABS
Objective: The potential of marine crabs as a source of bioactive products is largely unexplored. Methods: Portunussegnis crabs were collected from the northern coast of Persian Gulf. Antimicrobial activities of hepatopa...
A RAPID ISOCRATIC HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC-UV) METHOD FOR THE QUANTIFICATION OF RITONAVIR IN HUMAN PLASMA
Objective: An accurate, simple, and rapid HPLC-UV based method for the quantitative determination of ritonavir (RTV) in human plasma is developed.Methods: The method involved deproteinization of the sample with 0.125N Na...