Investigation of the Region of Interest by Computed Tomography for Subclinical Hypothyroidism
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 8
Abstract
We retrospectively investigated all of the patients who were evaluated for their thyroid function and underwent thoracic computed tomography (CT) in the emergency department of Juntendo University Hospital between April 2011 and April 2013. The subjects were divided into two groups: the SH group included subjects who received a diagnosis of subclinical hypothyroidism (SH), while the Control group included subjects who had a normal thyroid function. The definition of SH was a normal-range free T4 level and thyroid-stimulating hormone (TSH) over 5 mIU/L. The patients’ age, sex, underlying diseases and values of TSH, free T3, free T4 as well as the average CT value of both thyroid glands and the presence of contrast between the thyroid gland and sternocleidomastoideus muscle were compared between the two groups. There were 5 subjects in the SH group and 22 in the Control group. There were no significant differences between the two groups with regard to the age, sex, underlying diseases or level of free T4. However, the level of free T3, CT value and the frequency of positive contrast between the thyroid gland and sternocleidomastoideus muscle in the SH group were significantly smaller than in the Control group, while the level of TSH in the SH group was significantly greater than in the Control group. This is the first study to demonstrate a low density of the thyroid gland in patients with SH. Even the accidental detection of SH by CT may be useful for managing patients.
Authors and Affiliations
Youichi Yanagawa MD. PhD, Hiroki Nagasawa MD. , Taishi Dotare MD. , Ikuto Takeuchi MD. , Kei Jitsuiki MD. , Shunsuke Madokoro MD. , Norihito Takahashi MD. , Hiromichi Ohsaka MD. , Kouhei Ishikawa MD. , Kazuhio Omori MD. PhD.
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