Investigation on the safety of regular plasma donors aged 56-60 years
Journal Title: Chinese Journal of Blood Transfusion - Year 2024, Vol 37, Issue 7
Abstract
Objective To investigate the safety of regular plasma donors aged 55 to 60, so as to provide reference for retention and recruitment of elderly plasma donors in China. Methods Plasma donors from 9 blood products manufacturing enterprises from 2018 to 2020 and the local general population were selected as the research objects. The total protein level, albumin and globulin ratio(ALB/GLB, A/G) and adverse reactions of plasma donation of regular plasma donors and local general population were retrospectively analyzed. Results The total protein level (g/L) and A/G of plasma donors aged 56 to 60 and the general population were 61.21±5.62 vs 60.04±6.93 and 1.610±0.299 vs 1.635±0.330, respectively, and the differences were statistically significant. The total protein level of regular plasma donors was higher than that of general population, but A/G was slightly lower than that of general population. From 2018 to 2020, there were a total of 23 056 302 plasma donations in 108 plasma stations, and adverse reactions occurred in 20 932 donations, with a total incidence of 0.09%, with no serious adverse reactions. Conclusion It is safe for regular plasma donors aged 55 to 60 to donate plasma, and the retention of them can alleviate the pressure of plasma supply.
Authors and Affiliations
Yang GAO, Kecheng DONG, Mingli MA, Yan DONG, Donghong FANG, Yumeng SU, Rong ZHOU, Demei DONG
Analysis of donation related vasovagal reactions in Hefei
Objective To explore the influencing factors and characteristics of blood donation-related vasovagal reactions in whole blood donation in Hefei city, and to put forward specific prevention measures. Methods Whole blood d...
Effect of USP9X on Akt phosphorylation and platelet function
Objective To explore the expression of USP9X in platelets and its effect on platelet function. Methods The expression of USP9X in human and mouse was evaluated by PCR and Western blot. Platelets from young and old mice w...
Preliminary discussion on the causes and influencing factors of blood discarding
Objective To conduct a retrospective statistical analysis of the blood discarding situation in Xuzhou Central Blood Station in the past 5 years, so as to explore relevant measures and strategies to reduce blood discardin...
Application of binomial distribution-based statistical process control method in blood quality control
Objective This study endeavors to introduce the statistical process control (SPC) method to analyze the quality control index concerning red blood cells in additive solution with leukocytes reduced, with the aspiration t...
Research progress of SMIM1 in Vel blood type, tumor and plasmodium infection
Small integral membrane protein 1(SMIM1) gene encodes Vel blood group antigen, and homozygous deletion of 17 bases pairs in its exon 3 leads to Vel negative phenotype. As a rare phenotype, accurate identification and pre...