Invitro and Invivo Antiasthmatic Activity of Ethanolic Bark Extract of Symplocos Racemosa
Journal Title: Scholars Academic Journal of Biosciences - Year 2016, Vol 4, Issue 5
Abstract
The aim of the present study was to evaluate invitro and invivo antiasthmatic activity of ethanolic bark extract of Symplocos racemosa. For invitro study, isolated guinea pig ileum was used and dose response curve of histamine in plain Tyrode solution and in Tyrode solution containing 25 μg/ml ethanolic barks extract of Symplocos racemosa were performed. For invivo study histamine induced bronchospasm was performed using histamine chamber. 250 and 500 mg/kg of ethanolic bark extract of Symplocos racemosa were used and chlorpheniramine was used as reference control. The mean exposition time and percentage protection were calculated to assess the antiasthmatic potential of Symplocos racemosa. In isolated guinea pig ileum preparation, Symplocos racemosa relaxed the muscle against histamine and in histamine induced bronchospasm, both the doses of Symplocos racemosa bark extract significantly increased the mean exposition time and the percentage protection compared to control. From the result it was concluded that, Symplocos racemosa bark extract exhibits antiasthmatic activity. Keywords:Symplocos racemosa, Antiasthmatic activity, Histamine, Chlorpheniramine
Authors and Affiliations
Latha M, Premlal KR, Lavanya Priya KP, Sengottuvelu S
Keywords
Related Articles
- EP ID EP372831
- DOI -
- Views 142
- Downloads 0
Ovicidal activities and developmental effects of the chitin synthesis inhibitors, Noviflumuron and Novaluron, on the pink bollworm Pectinophora gossypiella (Saunders) (Lepidoptera: Gelechiidae)
The pink bollworm Pectinophora gossypiella is one of the most destructive insects attacking cotton fields world-wide. The present study was conducted to evaluate the survival and developmental effects of the novel chitin...
Evaluation of Variations of Haematological Profile of Menopausal Women in Umuahia, Nigeria
Menopause comes with great anticipation. The anticipation could even cause unnecessary fear in the women. The study was done to ascertain the haematological profile of menopausal women as changes usually show in the bloo...
Induction of callus from leaf and petiole of the plant Coleus vettiveroids K .C. Jacob
Coleus vettivereoids K .C. Jacob belonging to the family Labiatae is a widely accepted plant known for its traditional uses such as antipyretic, antibacterial, anti-inflammatory etc. The present study aimed to evolve a p...
A Review of New Method of Cold Plasma in Cancer Treatment
Abstract: Cold atmospheric plasma (CAP) is a semi-ionizing gas with ions, electrons, and particles without charge such as atoms. CAP is produced by different methods such as atmospheric plasma jet (APPJ), pencil plasma a...
Bioactive Exopolysaccharides (EPS) Synthesized From Exiguobacteriumaurantiacum and Brevundimonasdiminuta with Myeloid Cancer Cells Inhibiting and Flocculating Activity
Exopolysaccharides (EPS) are polysaccharides secreted by certain bacteria. Exiguobacteriumaurantiacum and Brevundimonasdiminuta, isolated from Nador’sMarchica lagoon from soil and water samples were found to be capable...