Invitro Eff ects of our Spring Water on the Solubility of Uric Acid Stones: a Pilot Study
Journal Title: Journal of Clinical and Analytical Medicine - Year 2010, Vol 1, Issue 2
Abstract
Aim The aim of this study was to evaluate the infl uence of our spring water on urinary analytes and stone samples in (patient with) uric acid stone. Material and Methods Twenty patients with uric acid stones underwent a nutritional and metabolic evaluation at baseline and aft er a controlled diet including our spring water. Stone samples were also left in the usual water and in the spring water. The weights of stones were measured before and 7 days aft er incubation. Results In patients who drank spring water, there was a tendency for the mean urine pH to increase, the change was signifi cant statistically. On the other hand, urine citrate excretion signifi cantly also increased in these patients (p<0.005). The diff erences between initial and end-dry weights of stone examples were signifi cant statistically (p<0.05). Conclusion The results of our pilot study may help us to reduce uric acid stone formation and recurrence with the alkaline spring waters.
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