Iodine deficiency in pregnant women at first trimester in Ankara
Journal Title: Journal of the Turkish-German Gynecological Association - Year 2019, Vol 20, Issue 1
Abstract
Objective: Iodine deficiency in pregnant woman in Ankara was shown in previous studies. We aimed to conduct a study in a tertiary center to investigate the need for iodine replacement in our population. Material and Methods: This was a single tertiary center, non-interventional, retrospective, cross-sectional study. Data were retrieved retrospectively from 440 women who were in the first trimester in gestational age. Maternal iodine status, thyroid-stimulating hormone (TSH) levels and T4 levels were examined. Urinary iodine concentration (UIC) was calculated based on the Sandell-Kolthoff reaction, which is a colorimetric method. We excluded patients with previous or current thyroid disease. Thyroid hormones and TSH were measured using chemiluminescence immunoassays. Results: Iodine deficiency prevalence (urinary iodine <150 μg/L) was 84.7% in first trimester of pregnancy in our population. The median UIC was 81.6 (1-450) μg/L, indicating iodine insufficiency. All the patients declared iodized salt use. None of the patients were taking iodine replacement. The mean TSH level was 1.53±1.27 mIU/L, (0.01 mIU/L-14.74 mIU/L) and the mean T4 level was 12.51±5.01 mIU/L (7.09 mIU/L-23.7 mIU/L). The TSH levels of 56 patients were higher than 2.5 mIU/L. According to these results, 12.72% of the patients had subclinical hypothyroidism based on serum TSH and free thyroxine levels. Isolated hypothyroxinemia was present in one patient. Conclusion: Our study demonstrated that pregnant women still develop iodine deficiency in Ankara despite mandatory iodine salt use. Iodized salt use does not provide enough iodine supplement, especially in pregnant women. Iodine supplementation has been shown to enhance neurologic development and psychomotor performance. We suggest that iodine should be a part of routine laboratory evaluation at the first prenatal visit for its importance in early pregnancy. Also, iodized salt use education should be provided to women to eradicate iodine deficiency. Iodine supplements should be recommended to all pregnant women in addition to iodized salt.
Authors and Affiliations
Kazibe Koyuncu, Batuhan Turgay, Feride Söylemez
Keywords
Related Articles
- EP ID EP48648
- DOI 10.4274/jtgga.galenos.2018.2017.0150
- Views 243
- Downloads 0
The relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother
Objective: Pregnancy is one of the most stressful periods a woman experiences in her life. The present study was an attempt to determine the relationship between maternal stress during pregnancy and cortisol plus materna...
Why and how to proceed to an ultrasound-guided transvaginal drainage of tubo-ovarian abscesses (with demonstrative video)?
The treatment of the acute phase of complicated tubo-ovarian abscesses relies on antibiotics associated with surgical management in case of visible abscess, poor clinical tolerance and resistance to medical treatment. Tr...
A comparison of the risk of cesarean section in gestational diabetes mellitus patients supplemented antenatally with vitamin D containing supplements versus placebo: A systematic review and meta-analysis of double-blinded randomized controlled trials
The aim of this study was to study the role of vitamin D containing supplements in the risk of cesarean section (CS), a common complication in gestational diabetes mellitus (GDM) patients. An additional objective was to...
Effect of vaginal douching on vaginal flora and genital infection
Objective: "This study aimed at examining the effect of vaginal douching (VD), which is a traditional and cultural application, on the vaginal flora and genital infections. Material and Methods: This descriptive study i...
Iodine deficiency in pregnant women at first trimester in Ankara
Objective: Iodine deficiency in pregnant woman in Ankara was shown in previous studies. We aimed to conduct a study in a tertiary center to investigate the need for iodine replacement in our population. Material and Met...