IRON DEFICIENCY ANAEMIA- A RISK FACTOR FOR FEBRILE SEIZURE- A CASE CONTROL STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 44
Abstract
BACKGROUND The association between Iron Deficiency Anaemia (IDA) and Febrile Seizures (FS) is still obscure. The aim of this study is to assess any possible association between FS and IDA and to identify any contributory risk factors which if modified can prevent the occurrence of FS. MATERIALS AND METHODS A case control study was carried out at the Department of Paediatric Medicine, Vivekananda Institute of Medical Sciences (VIMS), Kolkata, India from 2013-2015 on children aged 6 months to 5 years with simple FS. Sample size was 100 cases and 100 age- and sex-matched controls. Patients were selected randomly with the help of computer generated random numbers. Children with atypical/ afebrile seizures, central nervous system infection, neurodevelopmental or haematological problems and children on iron supplementation were excluded. Consent of parents was taken, and ethical council of VIMS approved the study. Statistical analysis was done with the help of Epi Info (TM) 3.5.3. P < 0.05 was considered statistically significant. RESULTS The mean age (Mean±S.D.) of the patients was 2.18±1.22 years with a range of 0.56-4.83 years. The mean level of haemoglobin (Mean±S.D.) was 10.79±1.38 g/dL with a range of 6.1-14 g/dL. The mean level of total iron binding capacity (Mean±S.D.) was 380.48±64.43 µg/dL with a range of 266-489 µg/dL. The mean level of red blood cell distribution width (Mean±S.D.) was 14.74±1.11% with a range of 13.0-18.4%. The mean level of mean corpuscular volume (Mean±S.D.) was 73±6.98 fL with a range of 41.0-104.7. The mean level of ferritin (Mean±S.D.) was 48.33±25.41 ng/mL with a range of 13.0-190 ng/mL. CONCLUSION In this study, the incidence of IDA in the FC group was higher than in the control group.
Authors and Affiliations
Suparna Guha, Raja Bandopadhya
Keywords
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- EP ID EP549232
- DOI 10.14260/jemds/2018/1056
- Views 90
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