Iron (III) Phosphate Catalyzed the Synthesis of 4-quinolones
Journal Title: Chemical Methodologies - Year 2018, Vol 2, Issue 0
Abstract
New and efficient methods have been developed for the synthesis of 4-quinolones throughout Conrad–Limpach synthesis in diphenyl ether under reflux condition. This method possesses various advantages such as using a green and versatile catalyst, easy procedure, work up and separation, being free from column chromatography, and atom economic. Also, this kind of solvent and the reaction temperature has an important role in the yield of reaction. When toluene, ethanol, acetonitrile and chloroform were subjected as solvent in ambient temperature and reflux condition, the desired product did not result. Moreover, when diphenyl ether was employed in room temperature – at 100, 150 and 200 °C – it was observed that the product was obtained. Interestingly, the desired product was obtained in good yield under reflux condition in diphenyl ether.
Authors and Affiliations
Samaneh Samadi, Farahnaz K. Behbahani
Keywords
Related Articles
- EP ID EP648064
- DOI 10.22034/chemm.2018.60161
- Views 101
- Downloads 0
Investigation of NMR Parameters of para-Sulfonato-calix[4]arene by HF Calculation
Conformationally-rigid para-sulfonato-calix[4]arene (C28H24O16S4) was isolated. The NMR parameters of the structure of calix[4]arenes have been compared. The study of organic structures to form nanoporous materials is a...
Quantification of a Neuroprotective Agent Edaravone by Stability Indicating TLC Method and UV–Visible Spectroscopic Method in Bulk and Pharmaceutical Dosage Form
An accurate, sensitive, reproducible and precise stability indicating thin layer chromatographic method and UV-Visible spectroscopic method was established for the amelioration and validation of neuroprotective agent eda...
Conductance and FTIR Spectroscopic Study of Triple-ion Formation of Tetrabutylphosphonium Methanesulfonate in Methylamine Solution
Triple-ion formation of tetrabutylphosphonium methanesulfonate [Bu4PCH3SO3] in methylamine solution has been reported quantitatively by conductometric study, and the observation has evident from the qualitative analysis...
On The Characterization, Utilization and Wastewater Detoxification Potential of Pyrolysed Moringa oleifera Pods and Shells PART A: Sorbent Preparation and Characterization
In part A of this research, we reported adsorbent generation, characterization and optimization of factors affecting sorption. Destructive distillation technique was carried out for transforming biomass into biosorbents....
Improving degradation of polyethylene /acrylic dextrose with ground nut powder
The novel bio-based additives in the present research were incorporated into LDPE, LDPE in about 5 wt% subsequently processed to produce films of 50μ thickness. The bio-based additive such as acrylic dextrose (2.5%) /gro...