Is Glucose-6-Phosphate Dehydrogenase Deficiency a Risk Factor for Proliferative Diabetic Retinopathy in Male Patients with Type 1 Diabetes Mellitus in Basrah?
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 1
Abstract
Background: Diabetes Mellitus is a chronic and common disease with diabetic retinopathy a frequent long-term complication.Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most prevalent human enzyme defect. Both of these conditions are very common in our locality with many burdens on the patients' quality of life and health care services. Aim: To search for any significant association between G6PD deficiency and the development of proliferative diabetic retinopathy (PDR) among male patient with type 1 diabetes mellitus (T1DM). Method: A case-control study was conducted onNinety-four adult male patients with T1DM in Al Faiha Diabetes, Endocrine and Metabolism Center over a two-year period from October 2012 to October 2014. All patients are submitted to both funduscopicexaminations of their eyes and G6PD assay. Results: PDR is found among 7.6% of those who were G6PD sufficient in comparison to 42.9% of G6PD deficient (p-value<0.001). Conclusion: There is a significant association between G6PD deficiency status and the development of PDR in male patients with T1DM
Authors and Affiliations
Hussein Ali Nwayyir- MD
Keywords
Related Articles
- EP ID EP246235
- DOI -
- Views 70
- Downloads 0
A Rare Case of Spontaneous Conception in Untreated Wilson’s Disease
Wilson’s disease is a rare, autosomal inherited disorder of abnormal ATP7B gene resulting in excessive accumulation of copper in the liver and brain. It is suspected primarily in patients with degrees of liver failure or...
Role of Cryosurgery in Allergic Rhinitis- A Study of 50 Cases
Allergic rhinitis is one of the commonest diseases that otolaryngologist treat. Aims and objectives; 1.To evaluate the role of cryo surgery as one of the alternative modalities in management of chronic allergic rhinitis...
Correlation of Glycated Albumin Levels with Serum Adenosine Deaminase in type 2 Diabetes Patients
Background: In recent times Glycated Albumin routinely using as glycemic parameter to asses the status of diabetes complications. Type 2 diabetes mainly due to shortage or scarcity of insulin secretion. This insulin secr...
To Estimate the Prevalence of Bacterial Vaginosis in Labour
Background: Bacterial vaginosis (BV) is the most frequent type of vaginitis in women of reproductive age. BV is an imbalance in the ecology of the normal vaginal flora that is characterized by the depletion of lactobacil...
Profile of Patients with Acute Aluminuim Phosphide Poisoning in a Tertiary Care Institute of Haryana
Background: The Pesticides have proved to be a boon to the farming community to save the grains from pests and rodents etc. Aluminium phosphide (AIP), a solid fumigant pesticide is widely used as a grain preservative in...