Is Homocysteine a silent marker for cardiovascular disease?
Journal Title: International Journal of Biomedical and Advance Research - Year 2017, Vol 8, Issue 12
Abstract
Background: Cardiovascular disease (CVD) remains one of the leading causes of morbidity and mortality in India. Association between hyperhomocysteinemia and Metabolic Syndrome (MS) or its components in a population with or without cardiovascular disease is not well established. This study aims to check levels of homocysteine (Hcy) and its relationship with CVD. Aims and Objectives: To check Hcy levels in healthy adults and MS patients to reflect its association with CVD. Material and Methods: Case control study was done on 40 subjects patients with MS (n=20) and controls (n=20) of 30 - 60 years at Fr. Muller Medical College Hospital, Karnataka. Results: Homocysteine levels were significantly higher in MS group when compared to controls (p = 0.04). Conclusion: MS group had higher homocysteine levels along with blood glucose, triglycerides, total cholesterol when compared to controls. Elevated levels of Hcy can be a marker for cardiovascular disease. Furthermore, the results of this study suggest the overall role of homocysteine function on insulin resistance, and its association with cardiovascular parameters.
Authors and Affiliations
Nithin Varghese Abraham, Priyanka S. Bannikoppa, Pauline Anand
Keywords
Related Articles
- EP ID EP384624
- DOI 10.7439/ijbar.v8i12.4515
- Views 77
- Downloads 0
Evaluation of endothelial dysfunction in patients with type 2 diabetes mellitus Analysis of 100 cases
Background: Atherosclerosis which is a precursor for macro-vascular disease involves both functional as well as structural changes in the vasculature. Functional changes involve abnormalities in endothelium, vascular smo...
Reamed versus unreamed intramedullary nailing for the treatment of closed tibial fractures-A comparative study
Tibial fractures were the most common long bone fracture. These were treated by intramedullary nailing. Treatment of reamed versus unreamed intramedullary nailing was still controversial. This comparative study was condu...
Diagnstic accuracy of Computed Tomography- guided Fine Needle Aspiration Cytology of thoracic mass lesions-A study of 33 cases
Aim: The mediastinum harbors a mixed bag of tumors, which may create significant diagnostic dilemmas. These tumors have widely variable therapeutic and prognostic implications. Correct pre-operative cytological diagnosis...
Awareness, among primary health care physicians, of acute cyanide poisoning being a possible consequence of fire accidents
Objectives: To discern the degree of awareness amongst the primary health care physicians about the fact that cyanide poisoning is a possible consequence of fire accidents. Methods: Using an anonymous questionnaire, thi...
Complete blood count of blood donors in Antananarivo Madagascar
Objective: This study was conducted to determine the values of the blood count of blood donors in Antananarivo.Methodology: This is a descriptive and cross-sectional study from September 20th to November 09th, 2017 at th...