Is There a Correlation Between DAS28/RADAI in a Cohort of Rheumatoid Arthritis Patients Treated with Biological Therapy
Journal Title: Journal of Rheumatic Diseases and Treatment - Year 2016, Vol 3, Issue 1
Abstract
Aim: To describe the degree of activity of RA patients receiving biological agents co-monitored by rheumatologist and nurses. To assess RA activity using validated methods: DAS28, RADAI, visual analog scales (VAS), and to evaluate the correlation between them and the applicability in routine clinical practice. Methods: 114 patients with RA treated with biological agents, according to the American College of Rheumatology (ACR) 2010 criteria in shared nursing consultations from 12 Catalan hospitals were included. We analyzed whether there was good correlation between RADAI index and DAS28. Results: The mean value in the VAS scale was 2.85 (SD = 2.15), the mean RADAI self-assessment questionnaire level was 2.74 and the mean DAS28 index was 2.89. The majority of patients (63.1%) had a low disease activity (DAS28 < 3.2). 49/114 patients (44.1%) had a DAS < 2.6 (remission). Most patients treated with biologic agents have a good control of the disease, as measured by DAS28 objectively and subjectively by RADAI. Conclusions: The involvement of a multidisciplinary team (rheumatologist/ nursing) can coordinate patient care and establish consensus on the management of RA patients. Even though there are different tools of establishing the status of our patients, metrological evaluation with DAS28 is to date the most reliable, flexible and reproducible outcome measure.
MR Imaging of Degenerative Cartilage Lesions of the Knee Joint in Floor Layers and Graphic Designers
Introduction: Kneeling work leads to an additional risk of developing knee osteoarthritis (OA). Previous studies have primarily been based on radiography, but radiography is limited by its inability to visualize articula...
Chronic Large Joint Synovitis in Systemic Lupus Erythematosus: Finding What You Look For
A 30-year-Black African female was diagnosed with SLE when she presented with a Coombs positive haemolytic anaemia, lymphopenia, polyarthritis, oral ulcers and a malar rash. Her antinuclear antigen (ANA) was positive, sh...
Anti-inflammatory Effect of Antioxidant Pequi (Caryocar Brasiliense) Oil Capsules and Antioxidant Effect of Vitamin D and Physical Activity on Systemic Lupus Erythematosus Patients
Objectives: Verifying in SLE patients whether antioxidant supplementation with pequi oil capsules could reduce oxidative DNA damage and inflammation in SLE patients. Patients and Methods: A controlled randomized, crosso...
Meta-Analysis of the Clinical Efficacy of the Placebo Effect from Tumour-Necrosis-Factor Inhibitors to Treat Rheumatoid Arthritis after Methotrexate Failure
Introduction: Tumour-necrosis-factor (TNF) inhibitors, used to treat rheumatoid arthritis (RA), have non-specific (placebo effect) and specific effects. This meta-analysis appraises these effects within the first 3 month...
Association of Markers of Oxidative Stress, Medication Therapy and Life Habits in Fibromyalgia
Objective: To evaluate the association among genetic polymorphisms of glutathione S-transferase, oxidative stress, lifestyle habits and medication therapy in patients with fibromyalgia (FM). Patients and methods: A tota...