Is there any gender related difference existing in the presentation or management of patients with acute pulmonary embolism ? A prospective study
Journal Title: Journal of the Indian Medical Association - Year 2018, Vol 116, Issue 9
Abstract
Acute pulmonary embolism is an important cardiovascular cause of morbidity & mortality in general population. Whether gender has any implication in the clinical presentation and management of these patients is unclear. The objective of this study was to compare the clinical presentation and the therapeutic benefit in women and men with acute pulmonary embolism. In this study, 142 male & 85 female patients with acute pulmonary embolism were included and the clinical presentation and course after therapy were observed and compared. Results: Mean age of the study group (43.6 ± 14.7 versus 44.2 ± 13.9 years, p=0.66) and mean duration of symptoms (4 ±2 versus 6 ±4.4 days, p=0.04) before presentation in male patients were less than female patients. There were no significant differences seen in functional class, hypotension, electrocardiographic & echocardiographic features based on gender. Though there was non-significantly more death (13% versus 10%, p=0.74) but significantly more incidence of minor bleeding (25% versus 8%, p=0.045) in female patients than male patients. Other than increased incidence of minor bleeding, there were no significant differences in the clinical presentation, therapeutic benefit, and course after therapy, therefore, gender should not influence the decision to treat pulmonary embolism patients especially with thrombolytic agents but extra caution has to be taken while treating female patients.
Authors and Affiliations
Soumya Patra, Rabin Chakraborty
Keywords
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