Is There Any Relationship Between Serum Endocan Levels and Carotid Intima-media Thickness in Patients with Fibromyalgia?
Journal Title: Türk Osteoporoz Dergisi - Year 2019, Vol 25, Issue 2
Abstract
Objective: Although the pathophysiology of Fibromyalgia syndrome (FMS) has not yet been completely elucidated, it has been suggested that inflammation and endothelial dysfunction occur in patients with FMS. In recent years, endocan has been reported as an important biomarker for inflammation and endothelial dysfunction. It is important to assess carotid intima-media thickness (CIMT) in the evaluation of early atherosclerotic vascular diseases. In this study, we investigated this mechanism by measuring serum endocan levels and CIMT in patients with FMS and evaluated whether there is a correlation between them. Materials and Methods: Serum samples collected from 40 female patients diagnosed with FMS (the patient group) for the first time and 40 healthy female participants’ (the control group) endocan levels and CIMT ultrasonography were investigated, and the values of the two groups were compared. Results: Serum endocan levels and CIMT results were significantly higher in the patient group than in the control group (p<0.001). In addition, a very weak correlation was found between CIMT and endocan levels in patients with FMS. Conclusion: Increased subclinical inflammation, endothelial dysfunction, and early atherosclerosis play an important role in the pathophysiology of FMS. Increased endocan levels, CIMT, and the correlation between them will contribute to elucidating this mechanism.
Authors and Affiliations
Fatih Bağcıer, Fatih Hakan Tufanoğlu, Özgür Kadıçeşme
Keywords
Related Articles
- EP ID EP604632
- DOI 10.4274/tod.galenos.2019.16023
- Views 45
- Downloads 0
Osteoporotik Kırık Nedeniyle Kifoplasti Uygulanan Hastaların Klinik ve Demografik Özellikleri
Amaç: Bu çalışmanın amacı, osteoporotik kırık nedeniyle kifoplasti uygulanan hastaların demografik ve klinik özelliklerini belirlemektir. Gereç ve Yöntem: Retrospektif olarak planlanan bu çalışmaya 2011-2014 tarihleri ar...
Lomber Kemik İliğinin Difüzyon ve Kimyasal Kayma Manyetik Rezonans Görüntüleme Özellikleri; Osteoporozla Korelasyon
Objective: To investigate whether or not diffusion-weighted imaging (DWI) of vertebral bone marrow or dual-echo chemical shift imaging (CSI) achieved by magnetic resonance imaging (MRI) can be used in the diagnosis of os...
Evaluation of Eye Findings in Fibromyalgia Patients
Objective: Fibromyalgia (FM) is a rheumatic disease which exactly unknown etiology, causes widespread body pain. In FM patients, a large variety of ocular findings, especially dry eye, occur with and without other rheuma...
A Rare Cause of Low Back Pain in Pregnancy: Pregnancy Associated Osteoporosis
Pregnancy associated osteoporosis is a rare entity seen at the third trimester of first pregnancy or early postpartum period. It does not recur frequently in the subsequent pregnancies; however, it might lead to various...
Hemodiyalize Giren Son Dönem Böbrek Yetmezliği Hastalarında Üst Ekstremite Problemleri ve Fonksiyonları
Amaç: Bu çalışmanın amacı hemodiyalize giren kronik böbrek yetmezliği hastalarında üst ekstremitelere ait problemleri belirlemek, üst ekstremite ve el fonksiyonlarını değerlendirmek ve diyabetiklerle diyabetik olmayanlar...