Isolated Central Nervous System Blast Crises in Chronic Myelogenous Leukemia
Journal Title: GUJARAT CANCER SOCIETY RESEARCH JOURNAL - Year 2016, Vol 18, Issue 1
Abstract
Chronic myeloid leukemia (CML) is a chronic myeloproliferative disorder, currently treated with tyrosine kinase inhibitors. Uncontrolled CML eventually progresses to accelerated and blast crises, which is often medullary, and rarely extramedullary. It is extremely uncommon to have extramedullary blast crises, in the presence of major molecular response. The current case describes successful management of extramedullary blast crises of CNS in presence of major molecular response to Imatinib.
Authors and Affiliations
Avinash Talele, Asha Anand, Apruva Patel, Harsha Panchal, Sndip Shah, Sonia Parikh, Mukehsh Chaudhary, Pritam Kalaskar, Rahul Kulkarni
Keywords
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