Isolated Conjugated Hyperbilirubinemia in Seriously Ill Children – Don’t Forget Sepsis!
Journal Title: Open Journal of Pediatrics and Child Health - Year 2016, Vol 2, Issue 1
Abstract
Background: Jaundice is frequently associated with extrahepatic systemic infections. The important causes include increased bilirubin levels due to hemolysis, hepatic dysfunction, reduced excretion and cholestasis. Sepsis induced cholestasis has a unique pathophysiologic basis. Although common in gram negative sepsis among neonates, the clinical features of sepsis induced cholestasis are not widely recognized older children. Case report: We present a 6 year old, premorbidly asymptomatic boy with community acquired MRSA sepsis-pneumonia and ARDS (Acute respiratory distress syndrome) with isolated conjugated hyperbilirubinemia. A diagnosis of sepsis induced isolated cholestasis was considered after ruling out other possible causes of cholestasis. The hyperbilirubinemia improved with improvement in the primary pathology.
Authors and Affiliations
Mandal Anirban, Singh Amitabh
Keywords
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- EP ID EP554306
- DOI 10.17352/2640-7612.000009
- Views 42
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