ISOLATION AND CHARACTERIZATION OF SECONDARY METABOLITES FROM PITHECELLOBIUM DULCE BENTH FRUIT PEEL
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 11
Abstract
Objective: The present study describes the isolation and characterization of valuable secondary metabolites from the fruit peel of Pithecellobium dulce. Methods: Solvent extraction of the plant material using methanol followed by column chromatographic separation of the extract with solvents (Petroleum ether, ethyl acetate and methanol) of increasing polarity using silica gel yields four compounds (1-4). Results: The structures of the compounds stigmasterol (1), β-sitosterol (2), quercetin (3) and pinitol (4) were established on the basis of FTIR, 1H and 13C NMR; and mass spectra and in comparison with their literature values. Conclusion: Two sterols namely stigmasterol (1) and β-sitosterol (2), along with a flavonoid quercetin (3) and a cyclitol pinitol (4) have been isolated from the methanol extract of fruit peel of Pithecellobium dulce for the first time. Â
Authors and Affiliations
Sukantha T. A. , Shubashini K. Sripathi
Keywords
Related Articles
- EP ID EP578153
- DOI -
- Views 51
- Downloads 0
PREPARATION AND EVALUATION OF RAPIDLY DISSOLVING TABLETS OF RALOXIFENE HYDROCHLORIDE BY TERNARY SYSTEM FORMATION
Objectives: Enhancing the dissolution rate of raloxifene hydrochloride for the preparation of rapidly disintegrating tablets with subsequent rapid dissolution.Methods: Binary and ternary solid dispersions (SDs) with diff...
NEPHRO-PROTECTIVE ACTIVITY OF ISOLATED METHANOL FRACTIONS PHYTO-COMPOUND FROM BARK OF TERMINALIA ARJUNA
Objective: The aim of this study was to evaluate the antioxidant property of the isolated phytocompounds from TA (Terminalia arjuna) bark and in vivo study for nephro-protective and oxidative stress reducing activity in...
SYNTHESIS OF AMINO ACETYLENIC BENZOPHENONE DERIVATIVES AS H3-ANTAGONISTS
Objective: To synthesize new amino acetylenic benzophenone derivatives with significant H3-antagonist’s activity.Methods: Amino acetylenic benzophenone derivatives were synthesized from the reaction of 2-hydroxybenzoph...
UTILIZATION OF ETHNO-VETERINARY MEDICINAL PLANTS IN HASSAN DISTRICT OF KARNATAKA, INDIA
Objective: Present work deals with the studies on ethnoveterinary medicinal plants used by local people in Hassan district, Karnataka, India Methods: The survey was undertaken during 2015-2016 to collect the information...
METABOLITES ACTIVITY OF ENDOPHYTIC STREPTOMYCES SP. IPBCC. B.15.1539 FROM TINOSPORA CRISPA L. MIERS: ALPHA-GLUCOSIDASE INHIBITOR AND ANTI-HYPERGLYCEMIC IN MICE
Objective: This research work aimed to assess the capability of endophytic Streptomyces sp. IPBCC. b.15.1539 isolated from Tinospora crispa inproducing α-glucosidase inhibitor compound and examined the effect of its eth...