Isolation and characterization of Vasicine from Adhatoda vasica (Adusa)
Journal Title: International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL) - Year 2017, Vol 6, Issue 2
Abstract
The research work is related to an improved process of isolation & characterization of Vasicine from Adhatodha Vasica (Sanskrit: Adusa). Adhatodha vasica, commonly known as Arusa, is a valued herb in Ayurvedic medicine. Roots, leaves and preparations of the plant are traditionally used as tonic, antiasthmatic, analgesic, antiinflammatory and diuretic. A. vasica mainly contains Vasicine alkaoids including Vasicine which are specific to the Acantheceae family. Vasicinosides are biologically active secondary metabolites present in roots and leaves of A. vasica. In the present study, we have standardized the protocol for the isolation of Vasicine from the Adhatodha vasica punchang. Vasicine possess anti-inflammatory and antistress properties. This study contains newer and conventional method of isolation of Vasicine from Adhatodha vasaka as well Quantitative and qualitative techniques involved in purification of compound was followed throughout this research work. In this study, we have taken different trials based on hydro-alcoholic solvent composition. Based on different solvent extraction process pure 95% Vasicine was successfully isolated.
Authors and Affiliations
Bali Reddy Keesara| Institute of Pharmacy, Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu, Rajasthan, 313001, India, Rakesh Kumar Jat| Institute of Pharmacy, Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu, Rajasthan, 313001, India
Keywords
Related Articles
- EP ID EP16012
- DOI http://dx.doi.org/10.21276/IJRDPL.2278-0238.2017.6(2).2590-2
- Views 350
- Downloads 19
Speciation, biofilm formation and antifungal susceptibility of Candida isolates
Recently, an increase in the incidence of infections caused by fungi especially non-albicans Candida species has been reported. Several virulence factors like biofilm formation, toxin production and presence of adhesin...
EVALUATION OF ANTI-INFLAMMATORY POTENTIAL OF ETHANOLIC EXTRACT OF THE LEAVES OF RHIZOPHORA MUCRONATA, A SUNDERBAN MANGROVE
Objective: Biochemically unique mangrove plants are recognized worldwide for valuable medicinal actions. Experimental investigations of these pharmacological activities are needed for elucidation of cost effective new t...
Synthesis and biological activity of some novel Combretastatin analogues and related compounds
CA-4 is a biologically very active compound by binding to the colchicine binding site which lead to the inhibition of microtubule polymerization as well as showing antiagiogenic and anticancer effects by selectively sh...
Preparation of Sustained Release Microspheres of Aceclofenac: Characterization&in-vivostudies
Objective: To explore the sustained drug release model of Aceclofenac from microspheres to establish the result of hydrogel forming mucoadhesive polymers on drug release. Methods: Microspheres were produced by Emulsio...
Anti-stress effects of cinnamon (Cassia zelynicum) bark extract in cold restraint stress rat model
The present study aims at investigating the anti-stress effects of cinnamon (Cassia zelynicum) bark extract in cold restrained stress (CRS) model. The cinnamon anti-stress effect was characterized using ulcer scoring, a...