Isosorbide Mononitrate in Heart Failure with Preserved Ejection FractionA Review of Literature
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 8
Abstract
The objective of this review is to do a literature search on the effectiveness of isosorbide mononitrate in heart failure patients with preserved ejection fraction. Heart failure with preserved ejection fraction (HF-PEF) also known as diastolic heart failure is the clinical syndrome of heart failure associated with near-normal systolic function. It is a manifestation of signs and symptoms of heart failure with an ejection fraction greater than 45% and is characterised by reduced ventricular filling and elevated left ventricular filling pressure. There is an increased risk for the occurrence of congested cardiac failure or atrial fibrillation in such patients. Many drugs like diuretics, beta blockers, ACE inhibitors can be used to treat the above condition although nitrates being the most common choice of drugs to enhance activity tolerance in patients with heart failure and a preserved ejection fraction. This review aims at studying the effect of isosorbide mononitrate in heart failure patients with a preserved ejection fraction. Heart failure is a serious problem and can be fatal. Hence it is ideal to know the correct choice of medical treatment of such conditions.
Authors and Affiliations
Sruthi Srinivasan
Keywords
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