Issues Related With Calorie Restriction for Prevention and Treatment of Obesity
Journal Title: Obesity Research - Open Journal - Year 2016, Vol 3, Issue 2
Abstract
The prevalence of obesity has dramatically increased in the US and worldwide over the last 2 to 3 decades.1 Obesity is developed when lipids in the form of triacylglycerol are accumulated in the adipose tissue. However, obesity is not only a problem of energy imbalance since it is associated with changes of concentrations of circulating nutrients, metabolites, and adipokines. These adipokines, a type of cytokines secreted from adipocytes, are involved in regulation of satiety, inflammation, and other physiological functions.2 The increased levels of certain metabolites and decreased levels of essential nutrients in obesity are related with its complications as well. Therefore, obesity is a risk factor of type 2 diabetes, coronary heart disease (CHD), stroke, hypertension, and cancer, despite the fact as one of the major chronic diseases worldwide. Recently, obesity has been defined as a medical condition by the American Medical Association (AMA).
Authors and Affiliations
Yi Li
Keywords
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- EP ID EP554244
- DOI 10.17140/OROJ-3-e009
- Views 160
- Downloads 0
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