It’s Time to Examine the Impact of Genetic Susceptibility on the Incidence of Diabetes among HIV-Infected Individuals
Journal Title: HIV/AIDS Research and Treatment – Open Journal - Year 2016, Vol 3, Issue 1
Abstract
The remarkable advances in application of anti-retroviral therapy (ART) to treat HIVinfection has had a profound impact on the HIV epidemic as well as improved the quality and longevity of life for those who receive such treatment. Nonetheless, as individuals receiving ART live longer, they may develop chronic non-communicable disease at an increased incidence and/or severity when compared to non-infected and/or untreated individuals. Prime examples of this include cardiovascular and neurological disease, as well as metabolic syndrome and diabetes mellitus. Whether these growing disease burdens are identical in origin and outcome to disease in uninfected individuals, and whether ART impacts disease incidence and severity in addition to limiting HIV infection is often poorly distinguished. The data on type 2 diabetes mellitus (T2DM) provides a welcome case in point for this discussion.
Authors and Affiliations
Glen N. Gaulton
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